نتایج جستجو برای: riluzole

تعداد نتایج: 631  

Journal: :Journal of neurophysiology 2011
Renée D Theiss T George Hornby W Zev Rymer Brian D Schmit

The objectives of this study were to probe the contribution of spinal neuron persistent sodium conductances to reflex hyperexcitability in human chronic spinal cord injury. The intrinsic excitability of spinal neurons provides a novel target for medical intervention. Studies in animal models have shown that persistent inward currents, such as persistent sodium currents, profoundly influence neu...

Journal: :Revue Neurologique 2021

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by death of motor neurons in the cortex and spinal cord. This loss causes progressive weakness amyotrophy. To date, median duration survival patients with ALS, from first symptoms to death, estimated be 36 months. Currently treatment limited two options: riluzole which prolongs for few months edaravone availa...

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