Most patients with first-time kidney stones undergo limited evaluations, and few receive preventive therapy. A prediction tool for the risk of a second kidney stone episode is needed to optimize treatment strategies. We identified adult first-time symptomatic stone formers residing in Olmsted County, Minnesota, from 1984 to 2003 and manually reviewed their linked comprehensive medical records t...

Purpose This study aims to assess the predictive factors and treatment outcomes of Steinstrasse formation following shock wave lithotripsy (SWL) for ureter stone. Materials and Methods The medical records of 1,418 ureter stone patients who underwent one-session SWL from November 2005 to May 2013 at our medical institute were retrospectively reviewed. Finally, 551 patients met inclusion criter...

PURPOSE The aim of our study was to evaluate the association of several factors with spontaneous stone expulsion, including ureteral stone characteristics (size, location, hydronephrosis, perinephric stranding), types of medications prescribed (α-blocker, low-dose steroid), and other possible demographic and health-history factors (gender, age, serum creatinine, underlying diabetes mellitus [DM...

A new conodont species, Icriodus marieae, is described from pelagic limestone beds of the Carnic Alps (Austria). Specimens are obtained from the upper part of the Valentin Formation (Central Carnic Alps) and range from the latest Eifelian to middle Givetian. Significantly differing from other icriodontid conodonts is that the icriodontan element of the new species develops only three denticles ...

Many human diseases are caused by genetic mutations that decrease protein stability. Such mutations may not specifically affect an active site, but can alter protein folding, abundance, or localization. Here we describe a high-throughput cell-based stability assay, IDESA (intra-DHFR enzyme stability assay), where stability is coupled to cell proliferation in the model yeast, Saccharomyces cerev...

introduction: to compare outcomes of retrograde intrarenal surgery (rirs) with extracorporeal shock wave lithotripsy (eswl) as treatment of choice. methods: a total number of 46 patients with renal pelvic stones 10-20 mm and body mass index (bmi) >30 randomized in two groups underwent rirs and eswl from 2011 to 2014 and followed for 3 months. results: the patients mean ± sd age was 36.1 ± 13.1 ...

silicon dioxide or silica is the earth’s most abundant mineral. the primary pulmonary illness attributable to silica exposure is silicosis, which is observed in three forms: classic, accelerated and acute. a case of silicosis is presented in this article who has been working in a stone-cutting plant. he had suffered from symptoms of silicosis one year after employment in this plant (acute form)...

River confluence is a common feature of most irrigation and drainage channels and river systems, where tributary conflicts the main channel. In these section, rapid changes in velocity and discharge, sediment distribution and flow turbulent result in a deep confluence scour, a bar point in the separation zone at downstream of junction corner  and finally vortex flow. Thus, the main goal of this...