Compare the accuracy of two continuous-scale tests is increasing important when a new test is developed. The traditional approach that compares the entire areas under two Receiver Operating Characteristic (ROC) curves is not sensitive when two ROC curves cross each other. A better approach to compare the accuracy of two diagnostic tests is to compare the areas under two ROC curves (AUCs) in the...

BACKGROUND ROC analysis is widely accepted to assess and compare diagnostic validity of laboratory tests. Within the last few years, many new ROC programs have become available but have not been systematically evaluated. The aim of this study was to assess different ROC programs regarding their ease of use, mathematical correctness, final output, and their compatibility with other graphics prog...

In many practical classiication problems it is important to distinguish false positive from false negative results when evaluating the performance of the classiier. This is of particular importance for medical diagnostic tests. In this context, receiver operating characteristic (ROC) curves have become a standard tool. Here we apply this concept to characterize the performance of a simple neura...

Trauma and Injury Severity Score (TRISS) has been the benchmark of mortality risk in trauma centers for over 30 years. TRISS utilizes the Injury Severity Score (ISS) as an index of anatomical injury. This study investigated the efficacy of a new type of index of anatomical injury called the ICD-derived Injury Severity Score (ICISS) compared to the ISS using a logistic regression analysis and a ...

A generalized likelihood-ratio test (GLRT) detector is derived for detecting a spacetime signal in the presence of unknown subspace interference and unknown target doppler. The near optimality and constant false alarm rate (CFAR) property of the GLRT is shown by the relationship to the uniformly most powerful invariant (UMPI) test using a simple approximation. Examples are presented comparing t...

A mathematical description of fusion is presented using category theory. A category of fusion rules is developed. The category definition is derived for a model of a classification system beginning with an event set and leading to the final labeling of the event. Functionals on receiver operating characteristic (ROC) curves are developed to form a partial ordering of families of classification ...

INTRODUCTION To investigate whether respiratory variation of inferior vena cava diameter (cIVC) predict fluid responsiveness in spontaneously breathing patients with acute circulatory failure (ACF). METHODS Forty patients with ACF and spontaneous breathing were included. Response to fluid challenge was defined as a 15% increase of subaortic velocity time index (VTI) measured by transthoracic ...