This study aimed to investigate the role of TGF-β1 gene in SARS-CoV-2 infection. A total 178 individuals diagnosed with Covid-19 participated and, they were divided two groups related outcome (discharge or death). Genotyping rs1800468 and rs1800469 polymorphisms was performed samples, using allelic discrimination technique expression analysis 93 samples by Real Time PCR. There no association be...

Abstract Background Coronavirus disease 2019 (COVID-19) is a global health problem that causes millions of deaths worldwide. The clinical manifestation COVID-19 widely varies from asymptomatic infection to severe pneumonia and systemic inflammatory disease. It thought host genetic variability may affect the host’s response virus thus cause severity SARS-CoV-2 requires interaction with its recep...

In this article, we consider that, in practice, attack scenarios involving side-channel analysis combine two successive phases: an phase, targeting the extraction of information about target and identification possible vulnerabilities, exploitation applying techniques on candidate vulnerabilities. We advocate that protections need to cover these phases be effective against real-life attacks. pr...

Pomegranate is gaining popularity because of its proved nutraceutical properties and highly adaptable to different climates. In southern Jalisco, Mexico, 18 genotypes were characterized on the basis fruit characteristics (21 traits) AFLP (Amplified Fragment length polymorphism) markers. The first three components a principal analysis (PCA) explained 71.5% variation. most important variables rel...

objective: people are usually susceptible to carcinogenic aromatic amines, present in cigarrette smoke and polluted environment, which can cause dna damage. therefore, maintenance of genomic dna integrity is a direct result of proper function of dna repair enzymes. polymorphic diversity could affect the function of repair enzymes and thus augment the risk of different cancers. xeroderma pigment...

Recent studies show that NOTCH3 is involved in the glioma development and it is also a prognostic factor for glioma patients. However, the gene polymorphism of NOTCH3 in gliomas prognosis remains unknown.A total of 266 patients were enrolled into this study. The NOTCH3 gene polymorphism at 3 loci, including C>T polymorphism at nucleotide 381, C>A polymorphism at 474 and G>A polymorphism at 684 ...

Introduction: The coagulation factor 13 has a fundamental role in homeostasis, protective effects on thrombosis, and some other associated diseases. Due to increasing the chronic coagulability of major thalassemic patients, this study was conducted with aim determining the prevalence of Val34LeuFXIII polymorphism in the thalassemic patients. Materials and methods: The present case-control stud...

BackgroundIt has been confirmed that the connective tissue growth factor (CTGF) gene rs9402373 polymorphism is associated with fibrotic and inflammatory diseases. However, studies on relationship between polymorphisms in CTGF bowel disease (IBD) remain rare. Therefore, aim of this study was to assess association IBD susceptibility a Chinese population.Materials methodsTo establish an amplificat...

Bachground: Endometriosis is a disease of female genital system, which is defined by the presence of ectopic endometrial tissue outside the uterine cavity. IL-8 is an autocrine growth factor in the endometrium that contributes to the pathogenesis of endometriosis. The aim of this study was to investigate the association between -251T/A polymorphism in the IL-8 gene and endometriosis risk in Ira...