Mad1, a member of the Myc/Max/Mad family, suppresses Myc-mediated transcriptional activity by competing with Myc for heterodimerization with its obligatory partner, Max. The expression of Mad1 suppresses Myc-mediated cell proliferation and transformation. The levels of Mad1 protein are generally low in many human cancers, and Mad1 protein has a very short half-life. However, the mechanism that ...

We continue the classification of 2-dimensional scale-invariant rigid special Kahler (RSK) geometries. This classification was begun in [1] where singularities corresponding to curves of the form y2 = x6 with a fixed canonical basis of holomorphic one forms were analyzed. Here we perform the analysis for the y2 = x5 type singularities. (The final maximal singularity type, y2 = x3(x − 1)3, will ...

Wemake the statement rigorous that the Robinson–Schensted–Knuth correspondence is a tropicalization of the Dodgson condensation rule.

Xenopus oocytes can be induced to undergo meiotic maturation by treatment with either insulin or progesterone. In both cases, there is an increase in the overall rate of protein synthesis. Previous work in this lab has shown that the increase in protein synthetic rate in response to progesterone is (a) reflected in the activity of cell-free extracts and (b) exerted at a stage of the initiation ...

The RSK correspondence generalises the Robinson-Schensted correspondence by replacing permutation matrices by matrices with entries in N, and standard Young tableaux by semistandard ones. For r ∈ N>0, the Robinson-Schensted correspondence can be trivially extended, using the r-quotient map, to one between r-coloured permutations and pairs of standard r-ribbon tableaux built on a fixed r-core (t...

This paper highlights the connections between riffle shuffles and symmetric functions. We analyze the effect of a riffle shuffle followed by the RSK algorithm on the resulting permutation. The theory of shuffling also allows us to deduce certain quasisymmetric function identities. Finally, we present a result about the eigenvalues of the Markov chain induced by riffle shuffles.