Introduction: Psoriasis is a chronic, inflammatory skin disorder. Studies suggested dysregulations in cell programmed death keratinocytes may play role psoriasis. Previously, we found Oncostatin M (OSM) was overexpressed psoriatic lesions, and related to the expressions of cellular senescence autophagy markers. Therefore, hypothesized that OSM-regulated senescence-autophagy interaction maintena...

Background: The incidence of mucormycosis has risen more rapidly during the second wave compared with first COVID-19 in India. As other parts country, our state also experience surge cases among patients admitted hospitals. associated (CAM) which was new for whole medical community no prior experience. In this context a prospective descriptive study conducted.Methods: done at public sector tert...

Background: Astrocytes, which comprise ~90% of overall brain mass, are involved in brain immunity. These cells represent the non-professional class of CNS-resident APCs and may promote or inhibit CNS inflammation depending on the cytokines they secrete. IL-10 family of cytokines and their receptors, IL-20R1 and IL-20R2, may have a role in shifting astrocytes to a neuroprotective or neurodegener...

Background: Endometriosis is a complex disease that profoundly affects the quality of life in many women. This disease affects roughly one in ten women of reproductive age. Endometriosis induces a variable amount of inflammatory reaction in pelvic environment. An active immune system needs to recognize these inflammatory agents. Rapid innate immune system defenses against infections involve the...

Importance: Retinal vacuities can cause visual disturbances if not treated on time. Past researchers have shown an association of COVID19 with retinal vacuities. Objective: To evaluate the retina patients who tested RTPCR or Rapid Antigen test positive for COVID-19.Design: Cross-sectional studySetting: COVID-designated Government tertiary healthcare institution. Clinical evaluation suffered COV...

Background: The recent COVID-19 pandemic has taken over the world in enormous proportions like none other times. Vitamin D plays an essential role immune system and proven to have importance context of many respiratory infections. This study aims unveil possible correlation between vitamin levels disease outcome affirm hypovitaminosis as independent risk factor for severity COVID 19.Methods: We...

Background: Vitamin D deficiency is a major public health problem in all age groups. Through its immunomodulatory, anti-inflammatory and antioxidant effects it shown to have protective effect COVID affected children. The objective of the study was evaluate vitamin as risk factor for developing COVID-19 infection children relationship between clinical findings positive children.Methods: A retros...

AbstractIntroduction Containing COVID-19 requires broad-scale testing. However, sample collection qualified personnel and protective equipment may cause transmission. We assessed the sensitivity of SARS-CoV-2-rtPCR applying three self-sampling techniques as compared to professionally collected oro-nasopharyngeal samples (cOP/NP). Methods From 62 outpatients, we obtain...

To study the statistics of epidemiology, co-morbidities, clinical presentations, management and prognosis group. This is a retrospective conducted in tertiary care hospital South India, among 100 subjects, between May 2021 August when Mucor mycosis cases were frequently being diagnosed treated amongst COVID-19 infected patients. The results showed that 34.0% 51-60 years with 100% patients confi...

Background: There has been a growing interest in ivermectin ever since it was reported to have an in-vitro activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This trial conducted test the efficacy of mild and moderate disease 19 (COVID-19). Methods: A double blind, parallel, randomised, placebo-controlled among adult COVID-19 patients with severity on admission COVID...