antigenicity of proteins found in cow's milk is age dependent. this is primarily due to infants possessing a more permeable intestinal wall than that in adults. thus infants may acquire cow's milk allergy during their first year of life. while milk antigen specific ige may cause allergy in susceptible subjects, there is some evidence indicating that milk antigen specific igg may play some role ...

OBJECTIVE The aim of this study was to evaluate the suspicion of cow's-milk allergy in infants with unspecific gastrointestinal (GI) symptoms using the double-blind, placebo-controlled food challenge. METHODS A prospective cohort study, which recruited 57 consecutive children with gastrointestinally manifested symptoms suspected of cow's-milk allergy. All patients underwent a 5-day double-bli...

In patients with a cow’s milk protein allergy, the presence of these allergens in medicines, even trace amounts, can trigger serious allergic reactions. The study milk-related excipient prevalence 165 antiasthmatic based on information included Summary Product Characteristics, revealed lactose more than one third medicines. Since may suffer cross-contamination protein, results are an alert to h...

Due to the recent exponential increase in food allergies and atopic disorders, effective allergy prevention has become a public health priority in many developed regions. Important preventive strategies include the promotion of breastfeeding and vaginal deliveries, judicious use of perinatal antibiotics, as well as the avoidance of maternal tobacco smoking. Breastfeeding for at least 6 months a...

Successful therapy in cow milk (CM) protein allergy rests upon completely eliminating CM proteins from the child's diet: it is thus necessary to provide a replacement food. Donkey milk (DM) has recently aroused scientific and clinical interest, above all among paediatric allergologists. A deeper knowledge of proteins in DM is necessary to evaluate the immunological and physiological properties ...

The determinants of wheezing and allergy were investigated in 453 children with a family history of allergic disease. A randomised controlled trial examined the effects of withholding cows' milk protein during the first three months of life and replacing cows' milk with soya milk. The children were followed up to the age of 7 years. Withholding cows' milk did not reduce the incidence of allergy...

BACKGROUND Due to the age when it becomes apparent and the treatment needed, cow's milk proteins (CMP) allergy requires an accurate diagnosis to avoid labelling infants falsely as allergic and subjecting them to unnecessary diets. The objective of this multi-centre study carried out at the Allergy Units of 14 Children's Hospitals was to discover the epidemiological, clinical and evolutionary ch...

Food allergy is common in children and young adults and may be difficult to diagnose and is at present treated with avoidance of the food in question. The aim of this report is to share our clinical experiences monitoring omalizumab treatment by basophil allergen threshold sensitivity, CD-sens. Five children, 6-16 years of age, with a severe milk allergy including episodes of anaphylaxis and Ig...

Cow’s milk allergy (CMA) is one of the most frequent food allergies in childhood with an estimated prevalence of 2% in infants. As observed in the natural course of this disease, CMA has a good prognosis and more than half of the children reach the tolerance before school age. Otherwise, many different factors can modulate the natural history of CMA. Clinical and laboratory data suggest that ma...