Cancer stem cells (CSCs) are a small proportion of tumor cells that may be responsible for tumor metastasis and recurrence. Our recent research indicated that longikaurin A (LK-A) exhibited anti-tumor activity in nasopharyngeal carcinoma (NPC) both in vitro and in vivo. Here, we further investigated whether LK-A could suppress the stemness of NPC cells. Sphere formation assay was used to assess...

The signal recognition particle (SRP) from Escherichia coli consists of 4.5S RNA and protein Ffh. It is essential for targeting ribosomes that are translating integral membrane proteins to the translocation pore in the plasma membrane. Independently of Ffh, 4.5S RNA also interacts with elongation factor G (EF-G) and the 30S ribosomal subunit. Here we use a cross-linking approach to probe the co...

To understand how chloroplast mRNAs are translated into functional proteins, a detailed understanding of all of the components of chloroplast translation is needed. To this end, we performed a proteomic analysis of the plastid ribosomal proteins in the small subunit of the chloroplast ribosome from the green alga Chlamydomonas reinhardtii. Twenty proteins were identified, including orthologs of...

Increasing evidence has demonstrated a significant role for long non-coding RNAs (lncRNAs) in tumorigenesis. However, their functions in nasopharyngeal carcinoma (NPC) metastasis remain largely unknown. In this study, a model comparing high and low metastatic NPC cell lines (5-8F vs. 6-10B and S18 vs. S26) was constructed to determine the expression profile of lncRNAs using the microarray analy...

We present an attack on Salsa20 reduced to five of its twenty rounds. This attack uses many clusters of truncated differentials and requires 2 work and 2 plaintexts. 1 Definition of Salsa20 Salsa20 [1] is a candidate in the eSTREAM project to identify new stream ciphers that might be suitable for widespread adoption. For convenience, we recap here the parameterized family of variants Salsa20-w/...

This study assesses the possibility of obtaining regenerated cellulose products (beads and films) from eucalyptus sawdust dissolving pulps produced by non-conventional processes, compared with a commercial pulp as reference. Eucalyptus were obtained soda pulping followed two TCF sequential bleaching processes OOpZ, OOp, cold extraction. The characterization involved alpha-, beta- gamma-cellulos...

Abstract. Suharjono, Yuliatin E. 2022. Bacteria communities of coffee plant rhizosphere and their potency as growth promoting. Biodiversitas 23: 5822-5834. This study aimed to investigate the soil bacteria evaluate in supporting growth. The was collected from Coffea canephora arabica Malang, East Java. bacterial genomic DNA extracted by FastDNA Spin kit while Illumina platform analyzed total gD...

Luteinizing hormone is known to stimulate the production of progesterone in the corpus luteum of several species (Mason et al., 1962; Major et al., 1967; Armstrong, 1968; Collett et al., 1973). The rate-limiting step of steroidogenesis in steroid-hormoneproducing tissues is thought to be cholesterol side-chain cleavage (Stone & Hechter, 1954; Hall & Young, 1968). It was therefore decided to mea...

Supplemental
Section
S1
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Genome
Sequencing
and
Assembly........................................... 2
 Supplemental
Section
S2
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Indel
Assessment
With
the
Neutral
Indel
Model ................11
 Supplemental
Section
S3
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Great
Ape
Divergence
Estimate
via
WGS
Read
Mapping..11
 Supplemental
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S4
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Short
Read
Sequencing................................................................13
 Suppl...

DNA from Drosophila egg chambers undergoing chorion gene amplification was analyzed using the two-dimensional gel technique of Brewer and Fangman. At stage 10, 34% of DNA molecules from the maximally amplified region of the third chromosome chorion gene cluster contained replication forks or bubbles. These nonlinear forms were intermediates in the process of amplification; they were confined to...