Vertebrates displaying seasonal shifts in reproductive behavior provide the opportunity to investigate bidirectional plasticity in sensory function. The midshipman teleost fish exhibits steroid-dependent plasticity in frequency encoding by eighth nerve auditory afferents. In this study, evoked potentials were recorded in vivo from the saccule, the main auditory division of the inner ear of most...

A 59-year-old woman presented with a recent onset of dyspnea and chest pain. Past medical history and cardiovascular examination were completely normal. Electrocardiography demonstrated sinus rhythm with left bundle branch block pattern. Transthoracic echocardiography (TTE) revealed a slightly reduced ejection fraction with hypokinetic septal and anterior walls. Parasternal short-axis imaging d...

A 65 year old woman was admitted to our hospital with dyspne. She had a medical history of hypertension. Her blood presure was 156/107 mmHg under medication. Physical examination and routine blood tests were normal. The electrocardiogram showed sinus rhythm. Standard anteroposterior chest radiography (Figure 1A) showed a widened mediastinum so a thoracic aortic aneurysm (TAA) was suspected. Tra...

Background The purpose of this study is to evaluate the impact multiple overlapping flow‐diverting stents have on aneurysm occlusion rates and iatrogenic complications relative single stents. Methods A retrospective review a multicenter database from 2012 2020 was performed identify saccular aneurysms treated initially with ≥12‐month angiographic clinical follow‐up. Aneurysm as function stent n...

Second-order vestibular neurons (2 degrees VN) were identified in the isolated frog brain by the presence of monosynaptic excitatory postsynaptic potentials (EPSPs) after separate electrical stimulation of individual vestibular nerve branches. Combinations of one macular and the three semicircular canal nerve branches or combinations of two macular nerve branches were stimulated separately in d...

Background and Purpose—We sought to determine whether there are mutations in the COL3A1 gene in patients with saccular intracranial aneurysms with a type III collagen deficiency and whether there is an association between a marker in the COL3A1 gene and saccular intracranial aneurysms. One of the heritable factors possibly involved in the pathogenesis of saccular intracranial aneurysms is a red...

Research into the effects of weightlessness on rat vestibular maculae has consistently shown that ribbon synapses in hair cells of the utricular maculae exhibit statistically significant changes in number, kind, and distribution when rats are exposed to space flight (Ross, 1993, 1994, 2000). Synaptic plasticity was most evident when all type II hair cells of these maculae were considered and wa...

We report a 13-year-old girl with Loeys-Dietz syndrome (LDS) caused by a known transforming growth factor beta receptor II (TGFBR2) gene mutation, who developed aortic root dilatation and saccular aneurysm of the internal carotid artery. LDS is a rare, autosomal dominant aortic aneurysm syndrome with multisystem involvement. The disease is typically characterized by the triad of arterial tortuo...