A fetus with severe sacral agenesis and intrauterine growth retardation, ascertained at prenatal diagnosis, was found to be carrying an unbalanced form of a paternal balanced reciprocal translocation (7;19)(q36.1;q13.43), resulting in functional monosomy for 7q36.1-->qter. Necropsy confirmed that the fetus had isolated sacral agenesis type II. A critical region for autosomal dominant sacral age...

PURPOSE Conservative therapy and antimuscarinic agents are first line therapies for overactive bladder. Patients refractory to treatment are candidates for neuromodulation therapy. We estimated the costs and cost-effectiveness of percutaneous tibial nerve stimulation and sacral nerve stimulation. MATERIALS AND METHODS A Markov model was constructed to simulate the total costs and effectivenes...

STUDY DESIGN Retrospective case series. OBJECTIVE To report on the natural history and long-term outcome of a large series of consecutive primary sacral chordoma patients surgically treated at two reference centers. SUMMARY OF BACKGROUND DATA Sacral chordomas are rare tumors with poor long-term prognosis mainly caused by local failure. Till date, a few large series with long follow up are a...

Aim: Results of the surgical and medical treatments giant cell tumor bone (GCT) in terms local recurrence prognostic factors associated with are evaluated this study. Material Method: Patients treated either or methods for GCT between 2011 2021 were retrospectively evaluated. Gender age patients, localization tumors, existence pathological fractures, grade tumor, soft tissue expansion, resectio...

Two cases of sacral chordoma in a 7-year, 9-month-old boy and a 3-year, 4-month-old boy are presented. In addition to the typical histology of conventional chordoma, both tumors showed the less differentiated sarcomatoid appearance of atypical chordoma in the major portion. Immunohistochemically, in both cases neoplastic cells in areas of conventional as well as atypical chordoma were positive ...

PURPOSE To report results of sacral decompression and lumbopelvic fixation in neurologically impaired patients with highly displaced, comminuted sacral fracture-dislocations resulting in spino-pelvic dissociation. DESIGN Retrospective clinical study. SETTING Regional level one trauma center. PATIENTS Nineteen patients with highly displaced, comminuted, irreducible Roy-Camille type 2-4 sac...

AIM Sacral stress fractures are rare fractures presenting themselves with low back and groin pain. These fractures can be treated effectively using sacroplasty. MATERIAL AND METHODS The clinical and radiological data of three cases that underwent sacroplasty for sacral stress fractures were reviewed. The pain severity was assessed using the VAS system. The radiological investigation was perfo...

Neuromuscular stimulation via the sacral nerve roots is proposed for prevention of ischial pressure ulcers following a spinal cord injury (SCI). Acute effects of sacral functional magnetic stimulation (FMS) on seat interface pressure changes were investigated in five nondisabled volunteers. Similar effects were demonstrated with functional electrical stimulation in people with SCI who used a sa...

Tarlov or perineural cysts are nerve root cysts found most commonly at the sacral spine level arising between covering layers of the perineurium and the endoneurium near the dorsal root ganglion and are usually asymptomatic. Symptomatic sacral perineural cysts are uncommon but sometimes require surgical treatment. A 69-year-old male presented with pain in the buttock. He was diagnosed as having...

PURPOSE This study evaluates the effectiveness of total pelvic exenteration with distal sacrectomy for fixed recurrent tumor that developed from primary rectal cancer. METHODS We investigated surgical indications, techniques to minimize blood loss and reduce complications, and oncological outcomes in 57 patients who underwent total pelvic exenteration with distal sacrectomy between 1983 and 2...