Aim of this study is to confirm and investigate the diuretic effect of crocine which is the pharmacologically active component of Crocus sativus L. (saffron) and to study the possible mechanism of action in relation to urinary nitrite. Twenty four rats were divided into 3 groups; control, hydrochlorothiazide and crocine treated groups. Assay of the diuretic activity of crocine was performed by ...

Aim of this study is to confirm and investigate the diuretic effect of crocine which is the pharmacologically active component of Crocus sativus L. (saffron) and to study the possible mechanism of action in relation to urinary nitrite. Twenty four rats were divided into 3 groups; control, hydrochlorothiazide and crocine treated groups. Assay of the diuretic activity of crocine was performed by ...

Saffron (Crocus sativus Linn.) has been an important subject of research in the past two decades because of its various biological properties, including anti-cancer, anti-inflammatory, and anti-atherosclerotic activities. On the other hand, the molecular bases of its actions have been scarcely understood. Here, we elucidated the mechanism of the hypoglycemic actions of saffron through investiga...

Doxorubicin (DOX) is an anthracycline antibiotic routinely used as a chemotherapeutic agent for the treatment of solid tumours. However, DOX possesses an acute and cumulative cardiotoxicity due to free radical production. The present study was designed to investigate the possible protective effects of saffron (Crocus sativus) extracts against DOX-induced acute cardiotoxicity in isolated rabbit ...

Experimental studies demonstrated that saffron (Crocus sativus) given as a dietary supplement counteracts the effects of bright continuous light (BCL) exposure in the albino rat retina, preserving both morphology and function and probably acting as a regulator of programmed cell death [1]. The purpose of this study was to ascertain whether the neuroprotective effect of saffron on rat retina exp...

UGT707B1 is a new glucosyltransferase isolated from saffron (Crocus sativus) that localizes to the cytoplasm and the nucleus of stigma and tepal cells. UGT707B1 transcripts were detected in the stigma tissue of all the Crocus species analyzed, but expression analysis of UGT707B1 in tepals revealed its absence in certain species. The analysis of the glucosylated flavonoids present in Crocus tepa...

traditional knowledge can be used as a source for development of new medicines. in the present study, we compare the data on saffron in razi's al-hawi book with modern scientific studies. a computerized search of published articles was performed using medline, scopus as well as native references. the search terms used were saffron, crocus sativus, crocetin, crocin, safranal, razi, and al-h...

Crocus (Crocus sativus L.) is a crop species cultivated for its flowers and, more specifically, for its red stigmas. The flower of crocus is bisexual and sterile, since crocus is a triploid species. Its perianth consists of six petaloid tepals: three tepals in whorl 1 (outer tepals) and three tepals in whorl 2 (inner tepals). The androecium consists of three distinct stamens and the gynoecium c...

Production of Saffron (Crocus sativus L.) is expanding in both the traditional and non-native areas Jammu Kashmir, India. A study was carried out to develop a cost-effective production system module at ARSSSS, SKUAST-Kashmir, Pampore determine suitable corm weight planting density for saffron. The treatments current includes 3 levels (W1= < 8g, W2= 8-12g W3 = >12g) 5 densities viz., 15 lakh den...