Synovial Sarcoma (SS) is an aggressive, yet a relatively chemosensitive malignant mesenchymal neoplasm, which displays variable epithelial differentiation, and typically occurs in adolescents and young adults, most frequently in the lower extremities. SS is also reported at certain unconventional sites, where its inherent morphologic heterogeneity and overlapping histopathologic features with c...

We consider the problem of representing the spatial metabolic activity of sarcomas, an infrequent form of cancer affecting soft tissue, cartilage and bone. The typical treatment protocol for sarcoma tumors is surgical resection, generally preceded by chemotherapy in advanced cases. The median survival time for patients with sarcoma is about five years after surgery. Sarcoma patients are usually...

the primitive neuroectodermal tumor (pnet) belongs to a group of highly malignant tumors and is composed of small round cells of a neuroectodermal origin. categorized in the same tumor family as ewing sarcoma, the pnet is most likely to occur in bones and soft tissues. however, a small number of pnet cases arising in the pelvis have been reported as well. we present three cases of pelvic pnet: ...

Introduction: Alveolar soft part sarcoma is a very rare and aggressive type of sarcoma. Although its histology genetic characteristics have been identified, the benefits adjuvant radiotherapy for treatment are still being studied. Case presentation: In November 2007, 21-year-old woman presented with primary tumor in right thigh, histological immunohistochemical confirmation an alveolar sarcoma,...

OBJECTIVE To investigate the natural history of the triad of gastric stromal sarcoma, pulmonary chondroma, and extra-adrenal paraganglioma, a rare syndrome of unknown cause primarily affecting young women. METHODS Mayo Clinic records, the world literature, and the author's files were searched for patients with all or 2 of the 3 tumors. RESULTS Seventy-nine patients, 67 women and 12 men, wer...

Fundamentally, the present paper is concerned with both the state of the Rous sarcoma virus— masked or free—when the tumor is made to grow either in old or in young hosts, as well as with properties of the tumor itself, associated with the virus in either state. It is well known that the causative viruses of chicken sarcoma can vanish in the most unpre dictable way, so that filtrates from a...

Epstein Barr virus (EBV) is one of the most successful pathogens in humans with more than 95% human adult population persistently infected. EBV infects only and threatens these its potent growth transforming ability that readily allows for immortalization B cells culture. Accordingly, it also found around 1-2% tumors, primarily lymphomas epithelial cell carcinomas. Fortunately, however, our imm...

Participant in the process of normal bone remodeling is vitamin D, which, addition, has antiinflammatory (anti-cytokine), anti-proliferative and anti-tumor effects. Objective study to assess level 25-hydroxyvitamin D3 concentration blood serum before start treatment patients with benign, primary malignant metastatic tumors, taking into account polymorbidity. Materials methods. The following wer...

abstract background ewing sarcoma is the second most frequent primary bone cancer, following osteosarcoma in children. these tumors consist of small, round, or oval cells, which are believed to derive from parasympathetic autonomic nervous system. the common clinical presentations are pain, local tenderness, fever, palpable mass, and pathologic fractures. methods and materials this study descri...

Histological diagnosis of synovial sarcoma can be difficult. Genome-wide expression profiling has identified a number of genes expressed at higher levels in synovial sarcoma than in other soft tissue tumors, representing excellent candidates for diagnostic immunohistochemical markers. A tissue microarray comprising 77 sarcomas, including 46 synovial sarcomas, was constructed to validate identif...