We evaluated several methods for characterizing hypoxic chemosensitivity in the conscious rat. Adult Sprague-Dawley rats (n = 30) were exposed to normobaric hypoxia [inspired oxygen fraction (Fio2) 0.15, 0.12, and 0.09]. We measured ventilation (V̇e; barometric plethysmography), arterial oxygen saturation (SpO2; pulse oximeter), and oxygen consumption and carbon dioxide production (V̇o2 and V̇co2;...

AIM To determine normative data for arterial oxygen saturation, measured by pulse oximetry (SpO2), in healthy full term infants throughout their first 24 hours of life. METHODS Long term recordings of SpO2, pulse waveform, and breathing movements were made on 90 infants. Recordings were analysed for baseline SpO(2), episodes of desaturation (SpO2 /= four seconds, ...

Background and Aims One potential complication of acute respiratory distress syndrome (ARDS) is reduced dynamic compliance, saturation for peripheral oxygenation (SpO2) and increased sputum in patients that are mechanically ventilated. Airway clearance technique is the treatment given for patients on mechanically ventilator with ARDS. The purpose of the case series is to know the immediate effe...

BACKGROUND Beyond obesity, sleep apnea syndrome is frequently associated with excess abdominal adiposity that could contribute to the deteriorated cardiometabolic risk profile of apneic patients. METHODS The present study addressed the respective contribution of the severity of sleep apnea syndrome and excess abdominal adiposity to the cardiometabolic risk profile of 38 non obese men with pol...

In reviewing the article “Methemoglobinemia: Sudden Dyspnea and Oxygen Desaturation After Esophagoduodenoscopy,” in the August 2004 issue of RESPIRATORY CARE,1 I found the article suggested that, during the esophagoduodenoscopy procedure the patient’s blood oxygen saturation (measured via pulse oximetry) began to drop rapidly, and a saturation of 54% registered on the pulse oximeter while the p...

A two wavelength photometric fibre-optic reflectance sensor was developed for assessing abdominal organ perfusion. In vitro tests showed that reliable photoplethysmographic (PPG) signals and blood oxygen saturation (SpO2) values were recorded when the separation between emitting and receiving fibres was at 3mm and the emitting current was between 20mA-40mA. In a clinical study, good quality PPG...

The effects of inhalation anesthesia (2% isoflurane, sevoflurane, or enflurane) and intraperitoneal anesthesia with pentobarbital (65 mg/kg) were compared in rats using an electrocardiogram (ECG) and determination of blood oxygen saturation (SPO2) levels. Following inhalation anesthesia, heart rate (HR) and SPO2 were acceptable while pentobarbital anesthesia decreased HR and SPO2 significantly....