Objective: This project aimed to study early maladaptive schemas in adults with parents afflicted with schizophrenia.  Methods: In a causal-comparative study, a sample of 39 adults with one schizophrenic parent as the experiment group and 40 students without schizophrenic parents as the control group were selected. Both groups completed early maladaptive schema questionnaire. Descriptive ...

background: the purpose of this study was to test the hypothesis that the addition of buspirone, a partial agonist of 5ht1a receptor, to ongoing treatment with typical antipsychotics would improve the positive and negative symptoms in patients with chronic schizophrenia. materials and methods: in this study, 50 patients including 40 male and 10 female were recruited with chronic schizophrenia w...

objective: schizophrenia and other psychoses have devastating personal and social impacts and many efforts have been devoted to study ‎prodromal syndromes for psychosis in order to achieve earlier detection and interventions. however, only few studies have been ‎performed in developing countries on this subject, and there is a dearth of evidence in the iranian population. in this study, we ‎foc...

background: to evaluate public perceptions towards the causes of depression and schizophrenia and identifications of fac­tors resulting stigma towards mental ill. method: a cross-sectional study was conducted among the inhabitants of pulau-pinang, malaysia in march, 2009. a 24-item questionnaire was used to obtain respondent views. a non-probability (i.e convenient sampling method) was used to ...

objective: glutamate antagonists including anticonvulsant topiramate have been recommended for the pharmacological management of schizophrenia. methods: a randomized, double-blind, placebo controlled clinical trial was performed on 32 patients diagnosed with schizophrenia (18-45 years old). baseline information was gathered on demographic characteristics, vital signs, height, weight, smoking ha...

results we detected nine homozygotes in patients and 15 in control subjects. homozygosity was 7.08% and 11.8% in cases and control, respectively. nine types homozygote haplotype were detected in upper region of the cav1 gene in cases and controls. three haplotypes were common in cases and controls; four haplotypes were seen in controls only and two in cases. conclusions our findings implied a s...

Abstract In the treatment of persons with schizophrenia goal has gradually shifted from reduction symptoms and prevention relapse to recovery. However, this is achieved for a minority schizophrenia, while most them disorder still major cause disability, poor quality life premature death, presents considerable social economic costs. Studies aimed at identifying variables significant impact on ou...

objective(s):the hippocampus has been implicated in pathophysiology of schizophrenia. prenatal stress is a contributing risk factor for a wide variety of neuropsychiatric diseases including schizophrenia. this study examined long-term effects of prenatal restraint stress on the stereological parameters in the cornu ammonis (ca) of adult male rats as an animal model of schizophrenia. materials a...

objective: the methylenetetrahydrofolate reductase (mthfr) gene polymorphism c677t is suspected to be a risk factor for psychiatric disorders, but it remains inconclusive whether the mthfr polymorphism c677t is imputed to vulnerability to schizophrenia and bipolar disorder. method: we prompted impetus to appraise this polymorphism in an iranian population. therefore, 90 patients with bipolar di...

Introduction: Schizophrenia is one of the mental disorders classified as highly incapacitating, promoting a greater exclusion this individual from his tasks performed, and social life. The definition diagnosis, although necessary, causes changes not only for individual, but also affects family. Objective: This article aims to investigate occurrence overload in family caregivers individuals diag...