neuroprotective effect of the extract from aerial parts of scrophularia striata boiss(scrophulariaceae) was investigated against glutamate-induced neurotoxicity on cultured rat pupscerebellar granule neurons (cgns). cgns from 8 days old sprague-dawley rat were preparedand cultured. the experiments were performed after 8 days in culture. the plant was collected fromthe northeastern part (ruin re...

Description Diosmin is a naturally occurring flavonoid glycoside that can be isolated from various plant sources or derived from the flavonoid hesperidin. Diosmin was first isolated in 1925 from Scrophularia nodosa, and first introduced as a therapeutic agent in 1969. Diosmin is considered to be a vascular-protecting agent used to treat chronic venous insufficiency, hemorrhoids, lymphedema, and...

Loss-of-function siz1 mutations caused early flowering under short days. siz1 plants have elevated salicylic acid (SA) levels, which are restored to wild-type levels by expressing nahG, bacterial salicylate hydroxylase. The early flowering of siz1 was suppressed by expressing nahG, indicating that SIZ1 represses the transition to flowering mainly through suppressing SA-dependent floral promotio...

CHUL-HEE KIM,1 JANG H. YOUN,2 JOONG-YEOL PARK,3 SUNG K. HONG,3 KYONG S. PARK,4 SUNG W. PARK,5 KYO I. SUH,1 AND KI-UP LEE3 1Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul 140-743; 3University of Ulsan College of Medicine, Seoul 138-736; 4Seoul National University College of Medicine, Seoul 110-744; and 5Hallym University College of Medicine, Anyang 431-070, ...