This guideline includes statements and recommendations based on available, high-level evidence about the management of metastases in the central nervous system (CNS) in women with secondary breast cancer. The guideline provides health professionals with information designed to assist in making management recommendations for improved patient outcomes. CNS metastases in women with secondary breas...

conclusions spontaneous rupture of pyometra duo to cervical cancer in cases of acute abdomen in elderly patients should be considered. introduction pyometra is an accumulation of purulent material or pus in the uterine cavity. spontaneous perforation of uterus by pyometra is rare. this is a clinical presentation and management of a spontaneous perforation of uterine caused by pyometra. case pre...

with the prevalence of every type of cancer increasing globally, the inability to treat and the severe side effects caused by chemotherapy and radiotherapy are some of the biggest problems facing cancer patients and their physicians.1many herbal medicines have replaced their chemical rivals; for example, emetine lost its ground to metronidazole as an amoebicidal agent, and digoxin has given its...

BACKGROUND Very few studies have reported cancer outcomes of patients referred through different routes, despite the prominence of current UK cancer urgent referral guidance. AIM This study aimed to compare outcomes of cancer patients referred through the urgent referral guidance with those who were not, with respect to stage at diagnosis, survival, and delays in diagnosis. DESIGN OF STUDY ...

The present review introduces the aetiology and classification of cervical precancers. principles diagnosis based on colposcopy are reviewed. indications for targeted biopsy steps in diagnostic process Prophylaxis these diseases prevents cancer as high-grade precancerous lesions represent a direct precursor to cancer. basics primary secondary prevention, types screening, behaviour already-alert...

Background and objectives: To date, thousands of secondary metabolites have been isolated from plants and microorganisms and there is an unprecedented attention towards potential biomedical applications of natural compounds. In this study, cytotoxic properties of methanol extracts of Stachys obtusicrena, Aristolochia olivieri, Linum album, Dionysia sawyeri, Ajuga chamaecist...

introduction: cauda equina secondary to metastatic follicular thyroid cancer of the lumbosacral area is a rare entity.   case report: we report an unusual case of a 52-year-old male who presented with backache, lower limb weakness, and perianal numbness. a ct-scan of the lumbosacral area showed an enhancing mass at the l4, l5 and s1 vertebrae. histopathology after excision revealed a metastatic...

Despite their dose-dependent cardiotoxicity, anthracyclines are widely used for adjuvant chemotherapy of breast cancer. Secondary acute myeloid leukaemia (AML) is a rare long-term complication of the chemoand/or radiation therapies of breast cancer [1]. Treatment of such secondary AML, which usually requires additional courses of anthracycline-based chemotherapy and allogeneic haematopoietic st...

BACKGROUND To compare proton beam therapy (PBT) and intensity-modulated radiation therapy (IMRT) with conformal radiation therapy (CRT) in terms of their organ doses and ability to cause secondary cancer in normal organs. METHODS Five patients (median age, 4 years; range, 2-11 years) who underwent PBT for retroperitoneal neuroblastoma were selected for treatment planning simulation. Four pati...