Objective(s):Neurotoxicity of anticancer drugs complicates treatment of cancer patients. Vinblastine (VBL) is reported to induce motor and cognitive impairments in patients receiving chronic low-dose regimen. Materials and Methods: The effects of VBL treatment on motor, learning and memory functions of male and female Wistar rats were studied by behavioral related tests. Animals were given chro...

 EFL learners may advocate the desire to have a fulfilling experience while doing tasks rather than focus solely on finishing them. However, learners' perspectives have been virtually ignored in the classroom task implementation. Thus, the current study attempted to explore the perceptions of Iranian EFL learners towards listening pre-tasks in motivational and cognitive strategies instruction a...

Attention control (or executive control) is a higher cognitive function involved in response selection and inhibition, through close interactions with the motor system. Here, we tested whether influences of attention control are also seen on lower level motor functions of dexterity and strength-by examining relationships between attention control and motor performance in healthy-aged and hemipa...

The present study aimed to determine whether the general slowing hypothesis (GSH) could be extended to the motor domain by comparing cognitive and motor age-related slowing. To achieve this objective, we compared the slopes of Hick-Hyman's law and Fitts' law, in young and older adults. The general hypothesis was that, due to the dedifferentiation of cognitive and motor neural resources during a...

As the population of many industrialized countries ages, the number of older drivers on the roads increases. Statistics show that older drivers are at increased risk for involvement in fatal accidents. One explanation for this is the cognitive and motor declines associated with the aging process. As we age, performance on attention, memory and motor control tasks, three important components of ...

BACKGROUND The cognitive effects of dopaminergic treatment in Parkinson's disease (PD) are still controversial. OBJECTIVE To evaluate, in previously untreated patients with PD, whether chronic dopaminergic stimulation produces significant cognitive changes; whether they are sustained beyond the period of a few months; and whether the cognitive status of two motor-comparable groups is differen...

Parkinson's disease (PD) is attributable primarily to depletion of dopamine in the basal ganglia, but the full effects of this depletion are unknown. It is well known that PD involves motor slowing, and although it is not easy to distinguish between the motor and cognitive components of behavior, clinical observations suggest that cognitive processing may also be compromised. However, it remain...

Timed UP and Go Test (TUG) is conventionally used as predictor of falls in adults. Routine daily activities include multiple tasks performed concurrently. When two or more tasks (Dual/Triple test) needed to be carried out concurrently, task performance declined at least in one of them. Our study aimed to find temporal and demographic variations in the performance after adding a cognitive, motor...

In this study, we tested the effects of transcranial Direct Current Stimulation (tDCS) on two set shifting tasks. Set shifting ability is defined as the capacity to switch between mental sets or actions and requires the activation of a distributed neural network. Thirty healthy subjects (fifteen per site) received anodal, cathodal and sham stimulation of the dorsolateral prefrontal cortex (DLPF...