The long-term effects of vagus nerve stimulation (VNS) on seizure frequency were studied in 50 patients with epilepsy and learning disabilities. Mean observation time was 4.6 years. At follow-up, none of the patients was seizure-free, 25% had more than 50% seizure reduction, and 46% had some seizure reduction, but less than 50%. The discontinuation rate was 18%. Our results indicate that, like ...

OBJECTIVE To study the significance of new onset seizure in patient with human immunodeficiency virus (HIV) infection. METHODS Patients infected with HIV with the new onset seizure were enrolled in the study. Seizure type was classified. Adequate work up was done to search for a cause of their initial seizure. All patients were administered antiepileptic drugs in addition those detected to ha...

PURPOSE IQ tests are frequently used in the preoperative neuropsychological assessment of candidates for anterior temporal lobectomy (ATL). We reviewed IQ test results and surgery outcomes to evaluate the roles of IQ tests in the preoperative work-up. METHODS A total of 205 adult patients who had undergone ATL and whose seizure outcomes were followed for 2 years after surgery were included. T...

OBJECT Although a number of recent studies on the surgical treatment of insular low-grade glioma (LGG) have demonstrated that aggressive resection leads to increased overall patient survival and decreased malignant progression, less attention has been given to the results with respect to tumor-related epilepsy. The aim of this investigation was to evaluate the impact of volumetric, histological...

OBJECTIVE To determine whether seizure semiology is reliable in localizing and distinguishing seizures at 2 independent brain foci in the same patient. DESIGN Two masked reviewers localized seizures from 2 foci by their clinical semiology and intracranial electroencephalograms (EEGs). SETTING Epilepsy monitoring unit of referral comprehensive epilepsy program. PATIENTS Seventeen consecuti...

PURPOSE Some patients with neurally mediated reflex syncope may be misdiagnosed as epilepsy because myoclonic jerky movements are observed during syncope. The seizure-like activities during the head-up tilt test (HUT) have been rarely reported. The purpose of this study was to assess the characteristics of these seizure-like activities and evaluate whether there are differences in the clinical ...

PURPOSE To determine the frequency, causes, risk factors and outcome following early posttraumatic seizure. METHODS A retrospective analysis of age, sex, mechanism of injury, type and onset of unprovoked seizure occurring within one week of injury, admission coma score, and Glasgow outcome score in patients with nonpenetrating head injury. RESULTS Eighty six (10.2%) of 845 head injuredpatie...

We report a case of early-onset dementia with subclinical seizures. Aggressive seizure control improved the patient's cognition. Commonly, an EEG is only performed following overt behavioral seizures. Therefore, subclinical seizures tend to be underdiagnosed. Serial or extended EEG should be seriously considered in patients with early-onset dementia.

Abstract Background Lacosamide (LCM) is a third-generation anti-seizure medication (ASM) approved for focal onset epilepsy in patients aged ≥4 years. Previous studies have reported an efficacy of LCM as add-on treatment brain tumour-related (BTRE). To date, there are no the literature focusing on lacosamide used monotherapy to treat BTRE. In our retrospective study we investigated and tolerabil...

The influence of end-expired carbon dioxide concentration (E'CO2) on seizure duration was studied in 30 depressed patients undergoing electroconvulsive therapy (ECT) on three separate consecutive occasions. Unpremedicated patients breathed 100% oxygen before the induction of anaesthesia with methohexitone and the provision of partial neuromuscular blockade with suxamethonium. They then received...