In this issue, Stranges and colleagues (1) report findings from the Nutritional Prevention of Cancer (NPC) trial that show an increased risk for diabetes among participants randomly assigned to receive supplements with 200 g of selenium daily for 7.7 years compared with placebo. This effect was largely limited to participants in the top tertile of plasma selenium level at baseline ( 121.6 ng/mL...

introduction and aims: both observational and experimental studies have shown that higher selenium status reduces the risk of upper gastrointestinal cancers in selenium deficient populations. recent cancer registry data have shown very different rates of esophageal cancer (ec) and gastric cancer (gc) in four provinces of iran, namely ardabil, mazandaran, golestan, and kerman. the aim of this st...

two experiments were conducted to evaluate the different levels of selenium supplements on performance, blood metabolites and nutrient digestibility in mehraban male lambs. the first experiment consisted of 18 lambs, 4-5 months of age and 35.9±2.7 kg average in weight randomly allotted to 3 treatments. treatments were: 1) control diet (a diet without selenium, containing 0.06 ppm of selenium), ...

selenium is a metalloid that it is antioxidant characteristics is proved for humans, animals and plants. however, some plants are known as hyper accumulators for selenium and sometimes seems to be useful for growth of some plants. in this paper, we have studied the effect of different selenium concentrations on growth and morpho-physiological characteristics of spinach. seeds of spinach were ge...

introduction: there are limited reports about selenium status in major thalassemia patients. the aim of this study is evaluation of selenium status in patients with major thalassemia south east of iran with large sample size and wide range of age. this study compared selenium status with other sites of the world. methods: in this study 369 cases that had major thalassemia for more than 5 years ...

background: adequate serum level of zinc and selenium is required for normal metabolic performance and successful fertility. the present study was conducted to evaluate the association of serum zinc and selenium in early stage of gestation with the incidence of miscarriage in iranian women. materials and methods: one hundred two females were studied in three matched groups. group 1 consisted of...

BACKGROUND/OBJECTIVES Significant changes have been reported in dietary habits and food availability in Iceland that would be expected to compromise selenium intake and status, especially among young people. These include substantial decreases in the consumption of fish and milk, as well as the selenium content of imported wheat. The aim of this study was to assess selenium in the diet and whol...

Studies were conducted to examine the effect of pre and post-treatment of selenium in mercury intoxication (20 micromole/ kg b.w. each given intraperitoneally) in mice in terms of lipid peroxidation (LPO), glutathione (GSH) content, activities of superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT) and mercury concentration in liver, kidney and brain. No significant alterati...