In genetic association studies, unaccounted population stratification can cause spurious associations in a discovery process of identifying disease-associated genetic markers. In such a situation, prior information is often available for some subjects' population identities. To leverage the additional information, we propose a semi-supervised clustering approach for detecting population stratif...

A large number of biomedical resources are publicly available over the Internet. This number grows every day. Biomedical researchers face the problem of locating, identifying and selecting the most appropriate resources according to their interests. Some resource indexes can be found in the Internet, but they only provide information and links related to resources created by the owner instituti...

Hydrological drought analysis using SDI index in Halilrud basin of Iran Abstract Nowadays, drought is considered as damaging environmental phenomenon which affects natural resources and social communities. Therefore it will be an important issues that magnitude and effects of these phenomena to be considered. To do this we used L-moment method for regional homogeneity testing. The Streamflow Dr...

Covering a convex body by its homothets is a classical notion in discrete geometry that has resulted in a number of interesting and long-standing problems. Swanepoel introduced the covering parameter of a convex body as a means of quantifying its covering properties. In this paper, we introduce two relatives of the covering parameter called covering index and weak covering index, which upper bo...

The GDP forecasting is a prior concern for each country, but also for an entire region composed by more countries with specific and different evolutions of GDP. The GDP predictions for the 27 European Union are based on two econometric techniques. It was proved, using accuracy indicators like U1 and U2 Theil’s coefficients and statistical tests (Morgan-Granger-Newbold test, Harvey-Leybourne-New...

In the paper we construct a topological fixed-point theory for a class of set-valued maps which appears in natural way in boundary value problems for differential inclusions. Our construction is based upon the notion of (U, V )-approximation in the sense of Ben-El-Mechaiekh and Deguire. As applications we consider initial-value problems for nonlinear evolution inclusions of the type x′(t) ∈ −A(...

Certain statistical models are described by a family of reversed submartingales. The main problem under consideration is to estimate maximum points of the associated information function. It turns out that some maximal inequalities are important to be established in this direction. In this paper we show that these inequalities remain valid for suitable chosen modifications of those families. Ho...

Let X be a convex subset of a locally convex topological vector space, let U ⊂ X be open with U compact, let F : U → X be an upper semicontinuous convex valued correspondence with no fixed points in U \U , let P be a compact absolute neighborhood retract, and let ρ : U → P be a continuous function. We show that if the fixed point index of F is not zero, then there is a neighborhood V of F in th...

AIM OF THE STUDY We evaluated the possible effects of comorbid diseases and functional capacity on the survival of elderly female patients with breast cancer. MATERIAL AND METHODS The study included 159 breast cancer patients aged 65 years or older. Functional status of the patients was evaluated using Katz's index of activities of daily living (ADL) and Lawton and Brody's Instrumental ADL (I...