Multilocular thymic cyst (MTC) and germ cell tumors are common diseases that impact the mediastinum. Correctly diagnosing these can be difficult because several other conditions mimic them. We report a male patient with MTC associated mediastinal seminoma. A needle biopsy of tumor revealed numerous epithelioid granulomas mimicked sarcoidosis or mycobacterial infection. However, large atypical c...

Spermatocytic seminoma (SS) is a rare testicular neoplasm characterized by a palpable, painless, slowly enlarging mass in the testis. Even more rare is a synchronous bilateral presentation. Only eight cases of bilateral SS have been reported in the literature, of which three cases were present with synchronous testis enlargement, and five were sequential. Here, we report an additional case of s...

Spermatocytic seminoma (SS) is a rare entity, accounting for 2%-12% of all seminomas; amongst those, fewer than 10% are bilateral. These may occur synchronously or metachranously. We report here a case of bilateral SS in a 63-year-old patient, who initially presented with bilateral testicular masses. In our search of the literature, this represents the fifth documented case of synchronous, bila...

A 31 year old male with a previous history of testicular seminoma with complete reponse after orchiectomy and three cycles of BEP scheme, was referred for 18F-FDG PET/CT with a standard procedure for progressive decline consistent in spinal pain, gait difficulty and Charcot’s neurologic triad (scanning speech, intention tremor and nystagmus) initiated eight month after third course of chemother...

Testicular germ cell tumours (TGCT) account for between 1% and 1.5% of male neoplasms and 5% of urological tumours in general. They are classified broadly into Seminoma, which resemble primordial germ cells (PGCs), and Non-Seminoma, which are either undifferentiated (embryonal carcinoma) or differentiated (exhibiting a degree of embryonic (teratoma) or extra-embryonic (yolk sac choriocarcinoma)...

BACKGROUND Seminoma stage I is the most frequent testis cancer and single-dose carboplatin (AUC7) is an effective and widely used adjuvant treatment. Underdosing of carboplatin by 10% has been shown to almost double the rate of relapse and hence correct dosing based on accurate GFR measurement is crucial. The gold standard of GFR measurement with a radiolabelled isotope is expensive and not rea...

BACKGROUND Germ cell testicular cancer (TC) patients have an increased risk of developing a contralateral TC. This paper presents a retrospective analysis of patients with bilateral TC from a database of a single center and aims to highlight the need for an individual approach. MATERIAL AND METHODS In the study period from January 1970 to June 2013, a total of 1,438 patients with primary TC w...

Extragonadal germ cell tumors are relatively rare tumors, which usually occur in the mediastinum or retroperitoneum. In this report, we present a case of primary seminoma arising in the pelvic cavity. A 58-year-old man with urinary retention and abdominal distension was admitted to our hospital. Computed tomography and magnetic resonance imaging demonstrated a large mass in the pelvic cavity. H...

Intra-scrotal testicular torsion of a seminoma is extremely rare and has been reported scarcely in literature. On the other hand testicular torsion by itself is rare in old age as well. We report a 63-year-old male who was presented to our Emergency Department with a right scrotal swelling and pain for 1 week. The patient had intra-scrotal testicular torsion of a seminoma which was overlooked i...

We report the case of a 33-year-old male presenting with bilateral gynaecomastia whose karyotype was mosaic with 60% of the cells showing an isochromosome for the short arm of the Y chromosome and 40% showing 45,X complement. Further investigation revealed evidence of a stage one seminoma of the right testis and complete azoospermia. He was treated with bilateral orchidectomy and adjuvant radio...