this paper is about discrete sensitivity analysis. a triangular bending element with constant moment and six degrees of freedom is used. the required derivatives for sensitivity analysis are calculated explicitly. these formulations, finite element method and sequential linear programming are utilized to find shape optimization of plate bending structures. the numerical examples, which show the...

We perform a large-scale study of intrinsically disordered regions in proteins and protein complexes using a non-redundant set of hundreds of different protein complexes. In accordance with the conventional view that folding and binding are coupled, in many of our cases the disorder-to-order transition occurs upon complex formation and can be localized to binding interfaces. Moreover, analysis ...