List of Papers This thesis is based on the following papers, which are referred to in the text by their Roman numerals. Serial sectioning of breast cancer sentinel nodes does not significantly improve false negativity rate. Manuscript. on behalf of the Swedish Breast Cancer Group and the Swedish Society of Breast Surgeons. Axillary recurrence rate 5 years after negative sentinel node biopsy for...

The arboviral surveillance program in California depends in part on sentinel chickens to detect western equine encephalomyelitis virus, St. Louis encephalitis virus, and West Nile virus activity. From 2000 through 2002, 1,578 serum specimens from 34 sentinel flocks in northern and southern California were tested for antibodies to Culex tarsalis salivary gland antigens. Sentinel chickens that we...

Let a1,a2,…,ak be positive integers with gcd(a1,a2,…,ak)=1. Frobenius number is the largest integer that NOT representable in terms of a1,a2,…,ak. When k?3, there no explicit formula general, but some formulae may exist for special sequences a1,a2,…,ak, including, those forming arithmetic progressions and their modifications. In this paper, we give power weighted sum nonrepresentable integers. ...

PURPOSE We aimed to develop and translate a CD20-antigen-targeted radiopharmaceutical, Technetium-99 m-labeled (99mTc) rituximab, for sentinel lymph node (SLN) detection. METHODS 99mTc-rituximab was synthesized and tested for stability in human serum. The binding affinity to CD20 was evaluated in Raji cells by flow cytometric analysis. Biodistribution and sentinel node mapping were carried ou...

BACKGROUND Although sentinel lymph node biopsy technique is the gold standard in the management of malignant melanoma and is gradually replacing conventional axillary dissection in breast cancer, its use in colorectal cancer is still controversial. The objective of this study is to demonstrate the feasibility and safety of sentinel node biopsy in the management of colorectal carcinoma. METHOD...

BACKGROUND The use of a dye and radiocolloid to detect sentinel lymph nodes in breast cancer increases the detection rates. However the use of either method alone does not modify the false negative rate. Therefore there is no formal contraindication for the exclusive use of dye to detect nodes. AIM To report a prospective analysis of the exclusive blue dye technique for sentinel node biopsy i...

The metabolic hormone leptin has been implicated in the pathogenesis of various malignancies and may contribute to the high rate of cancer in obese individuals. We reported that leptin and its receptor are expressed by melanoma tumors and cell lines, and that leptin stimulates proliferation of cultured melanoma cells. Here, we tested the hypothesis that leptin contributes to early melanoma prog...

Vulvar cancer is a rare gynecological malignancy with mainly lymphatic spread. Sentinel node mapping plays an important role in the management of this gynecological malignancy. In the current study, we reported our experience in sentinel node mapping of vulvar cancer and review the literature accordingly. Since the introduction of sentinel node mapping to the surgical oncology community of our ...

The aim of this study was to evaluate the possibility of identifying the sentinel lymph node and involvement of neoplastic cells in patients with endometrial carcinoma limited to the uterus, and also its correlation with the conditions of other pelvic and para-aortic lymph nodes. Forty patients with endometrial carcinoma, clinical staging I and II, were submitted to complete surgical staging th...