Sentinel lymph node (SLN) biopsy was first described by Morton et al. (1) in 1992 in patients with malignant melanoma. Many others over almost 100 y had made significant scientific contributions that ultimately led to the development of the technique (2–4); however, it was Morton’s group from the John Wayne Cancer Center that condensed the principle of the technique now used around the world. S...

In a health care system in which decreasing costs, increasing quality, and minimizing morbidity are emphasized, new, less invasive surgical techniques are gaining popularity. Sentinel lymph node biopsy is one such procedure used to treat many types of breast cancer. By performing a biopsy of this node, which receives lymphatic drainage from the tumor, the surgeon can predict the status of all n...

The technique of lymphatic mapping and sentinel lymph node (SLN) biopsy for melanoma has emerged during the last 2 decades as a minimally invasive approach to evaluate regional lymph node basins in patients with intermediate- and high-risk primary cutaneous melanoma and has changed our approach to the clinically negative lymph node basin in melanoma during the same period. This review focuses o...

ةيوافمللا ةدغلا هلازإ لاجم يف انتربخ نايب ضرعتسن :فادهلأا .ركبلما يدثلا ناطرس تاضيرم ىدل ةسرالحا دلاخ كللما ىفشتسم يف ةيعجرلما ةساردلا هذه تيرجأُ :ةقيرطلا رياني ينب ام ةرتفلا للاخ ةيدوعسلا ةيبرعلا ةكلملما ،ضايرلا ،يعمالجا ناطرسب ةضيرم 120 ةساردلا تلمش .م2014 ربمسيد و م2005 عم ةسرالحا ةيوافمللا ةدغلا ةلازإ ةيلمعل نعضخ يتلالا و يدثلا ةصالخا تامولعلما عمج تم .ةدغلا هذهل ينلاا يحيرشتلا صحفلا و ةسرال...

The axillary lymph node status is the most reliable prognostic indicator of recurrence and overall survival in patients with breast cancer. The current standard surgical procedure for the management of invasive breast cancer is the complete removal of the cancer with total axillary clearance. However, recently, selective sentinel lymph node mapping and biopsy is gaining acceptance as a useful a...

BACKGROUND AND METHOD This paper reviews and discusses the feasibility and accuracy of sentinel lymph node (SLN) biopsy in breast cancer. A standardized method of identifying the SLN and detecting micrometastases is suggested, along with a strategy for the elimination of routine axillary lymph node dissection (ALND). RESULTS Although the SLN can be identified successfully by experienced pract...

OBJECTIVES To report our experience in sentinel lymph node biopsy (SLNB) in early breast cancer.  METHODS This is a retrospective study conducted at King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia between January 2005 and December 2014. There were 120 patients who underwent SLNB with frozen section examination. Data collected included the characteristics of patients, index tu...

BACKGROUND Lymph node status is the key to determining the prognosis and treatment of cervical cancer. However, it cannot be assessed clinically, and testing for nodal metastasis is controversial. We sought to systematically review the diagnostic accuracy literature on sentinel node biopsy, positron emission tomography, magnetic resonance imaging and computed tomography to evaluate the accuracy...

The concept of breast cancer treatment is changed from maximal tolerable treatment to minimal effective treatment. There has been a change from axillary lymph node dissection (ALND) to sentinel lymph node biopsy (SLNB). The current theory of breast cancer spreading to the axillary lymph nodes is established that if the metastatic cancer cell has spread to the axillary lymph node. The first node...

Objective: To assess the accuracy of sentinel lymph node biopsy in breast cancer, therefore, reducing the morbidity of axillary clearance in patients having clinically impalpable axillary lymphnodes. Study Design: A Prospective study Place and Duration of Study: This study was conducted at the Department of Surgery, Unit II, Chandka Medical College / Hospital, Larkana from January 2014 to Decem...