the miru-vntr polymorphism and katg463 mutation are used to genotype the mycobacterium tuberculosis, but the correlation between them and inh-resistance were unknown. this study was aimed to explore whether etre polymorphism and katg463 mutation could predict the inh-resistance, and the relationship between etre polymorphism and katg463 mutation.the etre, katg463 mutation and drug resistance in...

materials and methods the l. tropica strain was attenuated using continuous passaging 20 times. the infectivity of l. tropica was confirmed in balb/c mice. the l. tropica resistant strain was produced in vitro using a continuous increase in drug pressure. the cross resistance of l. tropica to other drugs was also investigated. results after 20 continuous passages, the balb/c mice tested negativ...

conclusions the present study showed a high prevalence of aminoglycoside-resistance genes among mrsa isolates in two cities in iran. results the results of drug susceptibility testing showed that the highest rate of resistance was against erythromycin in tehran (84.4%) and gentamicin (71.7%) in sari. all isolates were sensitive to vancomycin, and all strains harbored the meca gene. the aac (6’)...

conclusions due to the increasing resistance of pathogens to usual empirical antibiotics, it is reasonable to stress upon preventive measures, so that a minimum number of neonates develop sepsis. results coagulase-negative staphylococci (cons) were the most prevalent pathogens isolated from blood specimens in early and late-onset disease. escherichia coli and klebsiella were the most causative ...

results among the 4,506 studied patients with urine cultures, 300 (6.65%) and 4,206 (93.35%) urine samples showed positive and negative bacterial growth, respectively. the rates of urine cultures with bacterial growth for women and men were 90.66% and 9.44%, respectively. with regard to the bacterial growth, 90.33% were gram-negative and 9.67% were gram-positive. the most common isolated agent ...

background: integrons are the major reasons of multidrug resistance (mdr) among enteropathogenic bacteria. occurrence of horizontal gene transfer between integron-carrying microorganisms and other enteric bacteria may increase the rate of emergence of integron-associated antibiotic resistance. objectives: the objective of this study was to investigate class 1 integrons among members of enteropa...

conclusions the results showed that e. coli isolated from patients with uti had eight virulence factors with high frequencies. moreover, these results alleged a direct connection between virulence factors and antimicrobial resistance in e. coli. results the frequency of virulence factors papc, afa, sfa/foc, fimh, hly, neuc, ibea, and iucc were 53.3%, 51.7%, 53.3%, 56.7%, 23.3%, 31.7%, 20%, and ...

References 1. Davis MA, Hancock DD, Besser TE, Rice DH, Gay JM, Gay C, et. al. Changes in antimicrobial resistance among Salmonella enterica serovar Typhimurium isolates from humans and cattle in the Northwestern United States, 1982-1997. Emerg Infect Dis 1999;5:802-6. 2. Sandvang D, Aarestrup FM, Jensen LB. Characterisation of integrons and antibiotic resistance genes in Danish multiresistant ...

Serotype IV group B Streptococcus (GBS) is emerging in Canada and the United States with rates as high as 5% of the total burden of adult invasive GBS disease. To understand this emergence, we studied the population structure and assessed the antimicrobial susceptibility of serotype IV isolates causing adult invasive infection in Manitoba and Saskatchewan, Canada, between 2010 and 2014. Whole-g...

The emergence of resistance to antimicrobial agents within the salmonellas is a worldwide and severe problem. A case of treatment failure due to the emergence of resistance to ceftriaxone in Salmonella enterica serotype Anatum was studied. S. enterica serotype Anatum and Escherichia coli, both of which are susceptible to ceftriaxone, were initially isolated from a diabetic patient hospitalized ...