نتایج جستجو برای: serum biomarkers
تعداد نتایج: 392736 فیلتر نتایج به سال:
There is a lack of biomarkers sepsis and the resuscitation status. Our objective was to prove that serum expression certain microribonucleic acids (miRNAs) differentially regulated in sensitive different regimes. Anesthetized pigs (Sus scrofa domesticus) received no treatment (n = 15) or intravenous live E. coli 24). The septic animals 0.9% saline at 4 mL/kg/h 8) (low group (LoR)) 10–17 (high (...
Many disease biomarkers are expressed at relatively low levels or are not secreted making them difficult to detect in serum or plasma. However, these biomarkers can stimulate a robust humoral immune response even if the antigens are expressed at very low levels. Because the immune system serves as a natural amplification system, antibodies to these biomarkers can be produced at detectable level...
BACKGROUND Sensitive and specific biomarkers for the early detection of esophageal squamous cell carcinoma (ESCC) are urgently needed to reduce the high morbidity and mortality of the disease. The discovery of serum microRNAs (miRNAs) and their unique concentration profiles in patients with various diseases makes them attractive, novel noninvasive biomarkers for tumor diagnosis. In this study, ...
Currently available studies have suggested that a number of exosome-encapsulated microRNAs (miRNAs) are recognized as stable biomarkers for cancers. However, little is known about the effect of exosomal miRNAs on colorectal cancer (CRC). The aim of study is to identify specific miRNAs in serum exosomes, which may serve as potential diagnostic and prognostic biomarkers and therapeutic targets fo...
colorectal cancer (crc) is a third most common epithelial carcinoma. crc is known to develop from the early precancerous lesion to full blown malignancy via definite phases due to cumulative mutations and aberrant methylation of number of genes. the use of serum biomarkers that is non-invasive to discriminate cancer patients from healthy persons will prove to be an important tool to improve the...
We compared hepatic and serum lipid changes in hepatocellular carcinoma (HCC) patients to have a better understanding of the molecular pathogenesis of this disease and discovery novel lipid biomarkers. Hepatic and serum lipid profiling was conducted in paired liver and serum samples from 50 HCC patients and 24 healthy controls. A total of 20 hepatic and 40 serum lipid signatures were identified...
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