The recently described IL-33 acts as a pro-inflammatory cytokine, inducing the expression of multiple responses in the target cells. Although a nuclear localization of IL-33 has been described, its exact functional relevance is presently unknown. The present study was conducted to analyze the effects of IL-33 on the TNF-α induced synthesis of the ...

Since the dawn of nuclear physics (d,p) reactions have been the main tool to extract spectroscopic factors (SFs) (we call them phenomenological SFs), which were compared with predictions of the independent-particle shell model (ISPM). Later on electron-induced breakup reactions and nucleon knockout reactions became new tool to determine the SFs. Reduction of the phenomenological SFs deduced fro...

In today’s competitive marketplace, to increase customer satisfaction and profitability, supply chain management has become more prominent. Therefore, thorough planning designing the by seeing all levels units are essential growing efficiency of entire chain. present study, an eight-echelon network is designed for a closed-loop agricultural These eight echelons consisting suppliers, farms, dist...

As the quality of crucial entities can directly affect that of software, their identification and protection become an important premise for effective software development, management, maintenance and testing, which thus contribute to improving the software quality and its attack-defending ability. Most analysis and evaluation on important entities like codes-based static structure analysis are...

An important problem in bioinformatics is the inference of gene regulatory networks (GRN) from temporal expression profiles. In general, the main limitations faced by GRN inference methods is the small number of samples with huge dimensionalities and the noisy nature of the expression measurements. In face of these limitations, alternatives are needed to get better accuracy on the GRNs inferenc...

Orbital frontal cortex (OFC) is known to play a role in object recognition by generating "first-pass" hypotheses about the identity of naturalistic images based on low spatial frequency (SF) information. These hypotheses are evaluated by more detailed (and slower) ventral visual pathway processes. While it has been suggested on theoretical grounds, it remains unknown whether OFC also receives p...

Owing to increase in desired user throughput and to the subsequent increase in network traffic, the number and density of cells in cellular networks have increased, especially starting with LTE. This directly translates into higher capital and operational expenses as well as increased complexity of network operation. To counter all three challenges, Self-Organized Networks (SON) have been propo...

INTRODUCTION The Social Functioning Scale (SFS) was designed to evaluate social functioning essential to schizophrenic patients. Its length may be difficult to use in clinical practice. The objective of this study was to develop and validate a short version of the SFS. METHODS Data from 445 patients with schizophrenia who came from two separate studies, one longitudinal (n=250) and one cross-...

There is growing evidence that activated synovial fibroblasts, as part of a complex cellular network, play an important role in the pathogenesis of rheumatoid arthritis. In recent years, significant progress has been made in elucidating the specific features of these fibroblasts. It has been understood that although macrophage and lymphocyte secreted factors contribute to their activation, rheu...

The ability of a cell to distribute contractile stresses across the extracellular matrix in a spatially heterogeneous fashion underlies many cellular behaviors, including motility and tissue assembly. Here we investigate the biophysical basis of this phenomenon by using femtosecond laser nanosurgery to measure the viscoelastic recoil and cell-shape contributions of contractile stress fibers (SF...