results overall, ≥ 2 mm shortening of the radius was seen in 28% of the patients, 53% had 2 - 5 mm radial shortening and 19% of the patients had more than 5 mm shortening of the radius. most of the participants had acceptable outcomes. the mean angulation was 6.28 ± 2.85 degrees and the mean shortening was 3.92 ± 2.22. thirty-nine percent of the patients had an angulation of less than 5 mm, 56%...

Characterization of local and global contractile activities in the myocardium is essential for a better understanding of cardiac form and function. The spatial distribution of regions that contribute the most to cardiac function plays an important role in defining the pumping parameters of the myocardium like ejection fraction and dynamic aspects such as twisting and untwisting. In general, myo...

The importance of the loss of ovarian function to the progression of hypertension and heart disease in women is controversial. We investigated whether ovariectomy would accelerate development of hypertension, congestive heart failure, and neurohumoral activation in adult spontaneous hypertension heart failure (SHHF) rats, a genetic model of heart failure. Six months after ovariectomy, no signif...

With aging, structural and functional changes occur in the myocardium without obvious impairment of systolic LV function. Transmural differences in myocardial vulnerability for these changes may result in increase of transmural inhomogeneity in contractile myofiber function. Subendocardial fibrosis and impairment of subendocardial perfusion due to hypertension might change the transmural distri...

The effects on myocardial mechanics of acute, artificial aortic and mitral regurgitation were studied in the dog to determine the manner in which the changes in load induced by valvular regurgitation alter ventricular performance. With mitral and aortic regurgitant volumes of approximately the same magnitude as the forward stroke volume, immediate increases occurred in total stroke volume, left...

BACKGROUND We evaluated the ability of electromechanical mapping of the left ventricle to distinguish between nonviable and viable myocardium in patients with ischemic cardiomyopathy. METHODS AND RESULTS Unipolar voltage amplitudes and local endocardial shortening were measured in 31 patients (mean+/-SD age, 62+/-8 years) with ischemic cardiomyopathy (ejection fraction, 30+/-9%). Dysfunctiona...

An echocardiographic study helps in the assessment of systolic and diastolic left ventricular function due to potential clinical implications over the treatment and the prognosis of different heart diseases. Systolic function depends on three factors: the left ventricular (LV) function, arterial coupling (ventriculoarterial coupling) and blood volume. In the particular case of the left ventricu...

The left ventricular dimension and posterior wall dynamics were studied by computer assisted analysis of M mode echocardiography in 25 normal children (group 1) and 32 transfusion dependent children with beta thalassaemia major who had no evidence of heart failure (group 2). Twenty seven of those in group 2 remained well but five died of cardiac decompensation within 12 months. Compared with gr...

The natural history of contraction abnormalities and their response after acute myocardial infarction in man were studied using radionuclide angiography. Sixteen patients were studied before and after sublingual nitroglycerin within 24 hours, 5-7 days and 4-6 weeks after the onset of chest pain. Within 24 hours, central chord shortening in the zone of infarction was reduced to 13.1 +/- 9.8%, bu...

SUlMMARY To assess the effects of a natural volume overload state (pregnancy) on left ventricular function we recorded echocardiograms each trimester (TM) and four to 12 weeks postpartum. Heart rate increased from 77 ± 2 (SEM) to 88 ± 2 heats/min (TM I vs TM 3, P < 0.01) and declined to 69 ± 2.0 beats/min postpartum (P < 0.05 vs TM 3). Despite these changes, end-diastolic dimension increased fr...