BACKGROUND Small for gestational age (SGA) infants have been reported to be at higher risk for sudden infant death syndrome (SIDS). OBJECTIVE To compare the risk of SIDS among SGA and large for gestational age (LGA) infants with that of death from other causes of sudden unexpected deaths in infancy (SUDI) and the residual "other" causes of infant death. METHODS The 2002 US period infant bir...

Stroke-induced immunodepression (SIDS) is an essential cause of poststroke infections. Pharmacological inhibition of SIDS appears promising in preventing life-threatening infections in stroke patients. However, SIDS might represent an adaptive mechanism preventing autoreactive immune responses after stroke. To address this, we used myelin oligodendrocyte glycoprotein (MOG) T-cell receptor trans...

Despite much research during recent decades, the etiology and pathogenesis of sudden infant death syndrome (SIDS) remain unknown. Because of the role of the cerebellum in respiratory and cardiovascular control, it has been proposed that it plays an important role in the pathogenesis of SIDS. To date, 5 postmortem studies on the cerebellum of SIDS cases have yielded conflicting results. Using a ...

AIMS To investigate patterns of infant growth that may influence the risk of sudden infant death syndrome (SIDS). DESIGN Three year population based case control study with parental interviews for each death and four age matched controls. Growth was measured from prospective weight observations using the British 1990 Growth Reference. SETTING Five regions in England (population greater than...

CONTEXT Sudden infant death syndrome (SIDS) is a leading cause of postneonatal infant mortality. Our previous meta-analyses showed that any breastfeeding is protective against SIDS with exclusive breastfeeding conferring a stronger effect.The duration of breastfeeding required to confer a protective effect is unknown. OBJECTIVE To assess the associations between breastfeeding duration and SID...

Surgically induced diffuse scleritis (SIDS) is a recognised but less well reported cause of pain and reduced vision following cataract surgery. We have previously reported on complications of conventional extracapsular cataract extraction in which SIDS was the second most common. Recently, we conducted an audit of patients who underwent phacoemulsification cataract extraction to compare the inc...

THE LEADING CAUSE of mortality during the first year of life, after the neonatal period, is the sudden infant death syndrome (SIDS), also known as cot or crib death.' Its incidence is close to 2 per 1000 live births in most countries, although in some, e.g., the Scandinavian countries, it is markedly lower. It is usually defined as the sudden death of any infant or young child, which is unexpec...

Public and professional awareness of sudden infant death syndrome (SIDS) has increased in the 28 years since the establishment of the National Sudden Infant Death Foundation, now called the National SIDS Alliance.' Similarly, awareness of child abuse has increased in the 30 years since the publication of the first article on the battered child. In the majority of cases, when an infant younger t...

Abstract Background Autonomic dysfunction has been implicated in the pathophysiology of Sudden Infant Death Syndrome (SIDS). Butyrylcholinesterase (BChE) is an enzyme cholinergic system, a major branch autonomic and may provide measure (dys)function. This study was undertaken to evaluate BChE infants young children who had died from SIDS or Unexpected Death. Methods We measured specific activit...

The recent US decline in sudden infant death syndrome (SIDS) rates may be explained by a shift in how these deaths are classified or reported. To examine this hypothesis, the authors compared cause-specific mortality rates for SIDS, other sudden, unexpected infant deaths, and cause unknown/unspecified, and they evaluated trends in the age and month of death for these causes using 1989–2001 US l...