AIM To evaluate the effects of chronic exposure to ethanol in the liver and the expression of inflammatory genes in zebrafish. METHODS Zebrafish (n = 104), wild type, adult, male and female, were divided into two groups: Control and ethanol (0.05 v/v). The ethanol was directly added into water; tanks water were changed every two days and the ethanol replaced. The animals were fed twice a day ...

Background/Aim. Selective intraarterial radionuclide therapy (SIRT) with Yttrium-90 (Y-90) microspheres is also known as radioembolization and delivers high doses of radiation to hepatic tumors with minimum healthy liver exposure. The aim of this study was to present our preliminary experience in the role of liver directed radiotherapy with Y-90 microspheres for the treatment of unresectable he...

A novel mechanism has been defined for controlling per-oxisome proliferator-activated receptors γ (PPARγ) activity in response to thiazolidinedione (TZD) ligands, in which deacetylation of PPARγ by SirT1 remodels the transcriptional complex. This change favors expression of genes associated with increased energy use and insulin sensitization in white adipose tissue (WAT), and is required for a ...

Purpose: Aging is related to the onset of sarcopenia. Understand how its development occurs by immunological factors oxidative stress. One main effects for a person reduction muscle function. Aerobic and resistance physical exercise can reduce progression stress and, consequently, sarcopenia.
 Materials Methods: Systematic review with sample six scientific papers published in academic jour...

Presenter: Armeen Mahvash MD | The University of Texas Anderson Cancer Center Background: HCC is often diagnosed when potentially curative resection or transplantation not feasible. Selective internal radiation therapy (SIRT) with 90Y resin microspheres (SIR-Spheres®) an established locoregional treatment option for unresectable regulatory approval outside the USA. SIRT has potential to deliver...