In general, skin squamous cell carcinoma (SCC) presents as papules or plaques with erythematous or pigmented appearance that may ulcerate the skin. Cellulitis caused by metastatic deposit from a known primary skin SCC has been reported once.1 We describe a patient who presented with cellulitis on the face that did not respond well to full course of antibiotics treatment, and turned out to be a ...

AIM The aim of the work was the presentation of one case with Acrodermatitis enteropathica. METHODS Acrodermatitis enteropathica is diagnosed based on the pedigree, typical clinical manifestations on the skin, laboratory results, small bowel biopsy, skin biopsy and kariotype. RESULTS The patient was a two years old male toddler, hospitalized due to skin changes, chronic diarrhoea and total ...

A 53-year-old female presented with itchiness in her back. She has a 5 years history of tightness the skin on face, neck, and torso bilaterally. did not have other symptoms suggestive systemic sclerosis (scleroderma), rheumatologic workup was negative. Skin biopsy showed increased dermal mucin confirming diagnosis scleredema. Further serum protein electrophoresis (SPEP) an M-spike, monoclonal g...

Neurofibroma is a tumor composed of a complex proliferation of neuromesenchymal tissue (Schwann cells, perineural cells, fibroblast, and mast cells). We report a 45-year-old female who had a slow growing, large, soft, pedunculated mass on her left lateral neck. A skin biopsy confirmed the diagnosis of neurofibroma.

We report a twenty-seven-year-old man with the absence of hair on the scalp and eyebrows, which began shortly after his birth. One of his brothers had this problem too. Considering clinical signs and skin biopsy report of the patient, a diagnosis of congenital atrichia was made. The latest findings on the genetic of this disease will be reviewed.

Diagnosis of small fiber neuropathy may be challenging due to subtle clinical signs and to the normality of nerve conduction studies. Skin biopsy is a non invasive method which allows to quantify intraepidermal nerve fiber density after a simple immunostaining. The values measured must ideally be compared to normative data obtained on control subjects in order to determine their significance. W...

INTRODUCTION The presence of eosinophilic bodies in a skin biopsy can be found in a variety of situations and this may present a challenge to the pathologist. The differential diagnosis of these eosinophilic structures include microorganisms such as histoplasmosis or cryptococcosis, fungi, Michaelis-Gutmann bodies, deposits of amyloid or immunoglobulins, colloid bodies or elastic bodies. CASE...

Dermatitis neglecta (unwashed dermatosis) presents as pigmented hyperkeratotic plaques with adherent scales which clinically resembles psoriasis. This condition is the result of avoiding washing the affected areas, so the lesions are characteristically resolved with normal washing or with gentle wiping from an alcohol swab. We report a 29-year-old man who presented with an asymptomatic hyperker...

Background: With the increase in life expectancy, middle aged and elderly people comprise a substantial percentage of the population worldwide. Since aging often manifests itself in the human skin, skin rejuvenation methods have gained a lot of popularity. Current medical modalities such as botulinum toxininjection, fillers, and laser therapy can provide symptomatic relief of skin aging s...