Methods The patients with AD admitted to outpatient clinic of pediatric allergy department from 1 January 2010 to 30 June 2010 were enrolled to the study. The disease severity and risk factors of the patients were assesed according to the SCORAD index. Skin prick test (SPT) for common food and inhalent allergens were performed to all patients with atopic dermatitis. The food specific IgE blood ...

Oral allergy syndrome (OAS) is occasionally observed following consumption of raw fruits in allergic adults. Since this phenomenon was commonly reported in Khorasan province of Iran; we intended to check if common diagnostic tests could be applied for differential diagnosis of OAS to grapes.IgE reactivity of 84 patients with OAS to grape and 34 patients with OAS to other fruits were analyzed by...

Cow’s milk allergy (CMA) is one of the most common food allergies in first years life. CMA classified as immunoglobulin E (IgE)or non-IgE-mediated reactions. IgE-mediated reactions are typically immediate onset, with symptoms manifesting within 2 hours after ingestion. However, delayed and mostly occur between 48 post exposure. This report describes a 17-year-old who presented long-standing his...

Oral allergy syndrome (OAS) is occasionally observed following consumption of raw fruits in allergic adults. Since this phenomenon was commonly reported in Khorasan province of Iran; we intended to check if common diagnostic tests could be applied for differential diagnosis of OAS to grapes. IgE reactivity of 84 patients with OAS to grape and 34 patients with OAS to other fruits were analyzed b...

The diagnosis of allergy is mainly based on the combination of clinical history data and results of skin prick tests (SPT) or in vitro IgE tests, including specific IgE measurement, and, as third level testing, challenges with the suspected allergens. The atopy patch test (APT) that assesses the type 4, delayed hypersensitivity, is insufficiently used. We review the data obtained in recent stud...

cow’s milk allergy (cma) is the most frequent food allergy in children and oral immunotherapy (oit) is a promising approach for treatment of patients. the most challenging cases are anaphylactic with coexisting asthma and proposing safe protocols is crucial especially in high risk groups. considering that cma varies among patients, an individualized oit protocol would be beneficial to achieve a...

Objective. To determine the diagnostic significance of methods allergological diagnostics: skin prick tests (SPT), quantitative determination specific immunoglobulin E (sIgE) and nasal provocative test (NPT) in children with allergy to house dust mites (HDM) diagnosed allergic rhinitis (AR) or AR combination asthma. 
 Methods. Patients underwent a targeted history taking for possible domes...

BACKGROUND Identifying toddlers at increased risk of developing persistent wheeze provides an opportunity for risk-reducing interventions. House dust mite (HDM) allergen sensitization might identify this group of high-risk children. OBJECTIVE We examined whether a positive skin prick test (SPT) to at least 1 of the 3 HDMs in wheezing toddlers, would serve as a predictor for persistent wheeze ...

BACKGROUND Immediate hypersensitivity to corticosteroids is reported to occur with an incidence of 0.1%. The largest previous case series reporting corticosteroid skin testing has seven patients. METHODS AND PATIENTS We identified 23 patients (mean age 50 years, 65% female) from Auckland City Hospital who underwent skin testing (ST) for suspected corticosteroid hypersensitivity between July 2...

BACKGROUND In a subgroup of patients with atopic eczema (AE), aeroallergens are relevant eliciting factors. The atopy patch test (APT) was proposed as inflammation model for AE. OBJECTIVE It was the aim of this study to investigate the effect of pretreatment with 1% pimecrolimus cream (Elidel) on the APT and skin prick test (SPT). METHODS In a randomized, controlled, double-blind study, 20 ...