نتایج جستجو برای: sle
تعداد نتایج: 10032 فیلتر نتایج به سال:
Systemic lupus erythematosus (SLE) is a predominantly female autoimmune disease that affects multiple organ systems. Herein, we report on an X-chromosome gene association with SLE. Methyl-CpG-binding protein 2 (MECP2) is located on chromosome Xq28 and encodes for a protein that plays a critical role in epigenetic transcriptional regulation of methylation-sensitive genes. Utilizing a candidate g...
Although liver dysfunction is not considered the main organ pathology or prognostic factor in patients with Systemic Lupus Erythematosus (SLE), it is not uncommon during the course of SLE. Liver complications in patients with SLE may be caused by lupus hepatitis (SLE-related hepatitis); autoimmune liver diseases, such as Autoimmune Hepatitis (AIH) and Primary Biliary Cirrhosis (PBC); viral hepa...
Background:Systemic lupus erythematosus (SLE) is an autoimmune disease with multiple organ involvement and periods of relapse and remission that mainly affects young women of childbearing age. In this regard the reproductive health is an important issue. Although diagnosis, treatment and management of pregnancy in SLE women have been improved recently, but the main concern is effects of SLE on ...
Introduction Systemic Lupus Erythematosus (SLE) is a complex autoimmune and inflammatory disease. Many studies show HLA alleles can be associated with SLE. The aim of this study was to determine the association of HLA-DRB1 alleles with juvenile- onset in Iranian children. Materials and Methods At a case – control study, 31 children with systemic lupus erythematosus (case group) who referred to ...
Background: To evaluate the possibility that prolactin is involved in the pathogenesis and flare-up of systemic lupus erythematosus (SLE).Methods: In this cross-sectional study we determined serum prolactin levels in sixty (60) serum samples from sixty patients diagnosed with SLE by the criteria of the American College of Rheumatology (ACR). All patients were females between 13-64 years of age....
Background & Aims: Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease, involving multiple organs and producing autoantibodies against different components of the cell. SLE is of unknown etiology with various clinical and laboratory manifestations. Different psychological disorders are seen in patients with SLE, including mood, anxiety, and cognitive disorders. This study w...
background patients with systemic lupus erythematous (sle) are more prone to atherosclerosis and cardiovascular diseases due to atherosclerosis and consequently death. objectives the aim of this study was to explore a possible relationship between the intima media thickness (imt) of carotid arteries and the levels of c-reactive protein (crp) in sle patients. patients and methods: sixty sle pati...
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