نتایج جستجو برای: slow twitch muscles

تعداد نتایج: 163389  

Journal: :The Journal of Cell Biology 1985
F H Schachat A C Canine M M Briggs M C Reedy

Two species of alpha-actinin from rabbit fast skeletal muscles were identified with a monospecific antisera. Designated alpha-actinin1f and alpha-actinin2f, their distribution in muscles does not correlate with histochemically defined fast fiber type. Rather, the presence of each correlates with Z-line width and with the expression of different thin filament Ca2+-regulatory complexes. alpha-Act...

Journal: :The Journal of Cell Biology 1965
Sally G. Page

The organisation of the myofibrils and the sarcoplasmic reticulum in frog slow muscle fibres has been compared with that in twitch fibres. It has been found that the filaments have the same length in the two types of fibre, but that there are differences in their packing: (a) in contrast to the regular arrangement of the I filaments near the Z line in twitch fibres, those in slow fibres are irr...

Journal: :The Journal of physiology 2004
Paul Gregorevic David R Plant Nicole Stupka Gordon S Lynch

Damaged skeletal muscle fibres are replaced with new contractile units via muscle regeneration. Regenerating muscle fibres synthesize functionally distinct isoforms of contractile and regulatory proteins but little is known of their functional properties during the regeneration process. An advantage of utilizing single muscle fibre preparations is that assessment of their function is based on t...

2016
Yoshiki Ohnuki Daisuke Umeki Yasumasa Mototani Kouichi Shiozawa Megumi Nariyama Aiko Ito Naoya Kawamura Yuka Yagisawa Huiling Jin Wenqian Cai Kenji Suita Yasutake Saeki Takayuki Fujita Yoshihiro Ishikawa Satoshi Okumura

Clenbuterol (CB), a selective β2-adrenergic receptor (AR) agonist, induces muscle hypertrophy and counteracts muscle atrophy. However, it is paradoxically less effective in slow-twitch muscle than in fast-twitch muscle, though slow-twitch muscle has a greater density of β-AR We recently demonstrated that Epac1 (exchange protein activated by cyclic AMP [cAMP]1) plays a pivotal role in β2-AR-medi...

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