This paper describes the main objectives, technical content, and status of H2020 project entitled “High-performance advanced methods experimental investigations for safety evaluation generic Small Modular Reactors (McSAFER)”. The pillars this are combination safety-relevant thermal hydraulic experiments numerical simulations different approaches evaluations light water-cooled (SMR). It goals, c...

BACKGROUND This study evaluated mortality among workers at a talc mining and milling facility. METHODS Subjects were white men actively employed between 1948 and 1989 and known to have been alive in or after 1950. Analyses assessed cancer mortality during the period 1950-89 (809 subjects) and non-cancer mortality during 1960-89 (782 subjects). RESULTS Comparisons with regional general popul...

The Smr family of multidrug transporters consists of small membrane proteins that extrude various drugs in exchange with protons rendering cells resistant to these drugs. Smr proteins identified to date have been found only in Eubacteria. In this work we present the cloning and characterization of an Smr protein from the archaeon Halobacterium salinarum, the first Smr in the archaeal kingdom. T...

While working underground, miners are exposed to a number of risk factors that have a negative impact on their health and may be a cause of an increased mortality in miners. The aim of the study was to compare total and specific mortality in black coal miners with acknowledged coal-workers' pneumoconiosis (CWP) and without CWP, and the mortality of the general male population in the Czech Repub...

Modulation of sensorimotor rhythms (SMR) was suggested as a control signal for brain-computer interfaces (BCI). Yet, there is a population of users estimated between 10 to 50% not able to achieve reliable control and only about 20% of users achieve high (80-100%) performance. Predicting performance prior to BCI use would facilitate selection of the most feasible system for an individual, thus c...

OBJECTIVES The ratio of observed to expected mortality (standardized mortality ratio, SMR), is a key indicator of quality of care. We use PreControl Charts to investigate SMR behavior over time of an existing tree-model for predicting mortality in intensive care units (ICUs) and its implications for hospital ranking. We compare the results to those of a logistic regression model. METHODS We c...

5 The utility of static and adaptive mesh refinement (SMR and AMR, respectively) are ex6 amined for idealized tropical cyclone (TC) simulations in a spectral element f -plane shallow 7 water model. The SMR simulations have varying sizes of the statically refined meshes 8 (geometry-based) while the AMR simulations use a potential vorticity (PV) threshold to 9 adaptively refine the mesh to the ev...

INTRODUCTION It has been nearly 20 yr since the first published astronaut mortality analysis. Using astronaut vital data and general population mortality rates, we calculate Standardized Mortality Ratios (SMR) for both total and specific causes of death among astronauts between January 1980 and June 2009 to look for changes in mortality patterns over time. METHODS Astronaut vital data were de...

OBJECTIVE To evaluate the validity of using the standardized mortality ratio (SMR) and the W statistic as risk-adjusted measures of hospital mortality to judge ICU performance. DESIGN APACHE (acute physiology and chronic health evaluation) II data were collected prospectively from the surgical ICU (SICU) at a single institution using all adult admissions (n = 6806) over an 8-year period (excl...

BACKGROUND Nasopharyngeal radium irradiation (NRI) was used widely from 1940 through 1970 to treat otitis serosa in children and barotrauma in airmen and submariners. We assessed whether NRI-exposed individuals were at higher risk for cancer-related deaths than were nonexposed individuals. METHODS We conducted a retrospective cohort study of all-cause and cancer-related mortality in 5358 NRI-...