. . . problems against the larger spectrum of general medicine." They have done this with almost the brevity of an abstract, yet with the clarity of a fuller presentation. The ample illustrations are well chosen and cleanly executed. Good bibliographies are supplied. The volume represents good current urological thinking and may be recommended as a manual for students and a reference for practi...

Referring expressions and other object descriptions should be maximal under the Local Brevity, No Unnecessary Components, and Lexical Preference preference rules; otherwise, they may lead hearers to infer unwanted conversational implicatures. These preference rules can be incorporated into a polynomial time generation algorithm, while some alternative formalizations of conversational impficatur...

In colorectal cancer (CRC), the treatment guidelines differ for Union International Contrè Cancer (UICC) stage II and III colon cancer patients. In patients with stage II colon cancer without risk factors such as T4 tumor, tumor perforation, emergency surgical procedure, or less than 12 removed lymph nodes, the low risk of recurrence is justifying no role of adjuvant chemotherapy. It would be c...

We present a concise outlook of particle physics after the first LHC results at 7-8 TeV. The discovery of the Higgs boson at 126 GeV will remain as one of the major physics discoveries of our time. But also the surprising absence of any signals of new physics, if confirmed in the continuation of the LHC experiments, is going to drastically change our vision of the field. At present the indicati...

The separation of sister chromatids at the metaphase-to-anaphase transition is triggered by a protease called separase that is activated by the destruction of an inhibitory chaperone (securin). This process is mediated by a ubiquitin protein ligase called the anaphase-promoting complex or cyclosome (APC/C), along with a protein called Cdc20. It is vital that separase not be activated before eve...