In Plato’s Meno the overarching question is whether virtue can be taught, and as Socrates and Meno explore this subject they are led to question the nature of teaching and learning in general. The following is a textual analysis into what Socrates believes to constitute teaching in the Meno, with the nature of learning also being tangentially addressed given the integral link between the two. A...

The polar flagellum of Vibrio alginolyticus is rotated by the sodium motor. The stator unit of the sodium motor consists of four different proteins: PomA, PomB, MotX and MotY. MotX and MotY, which are unique components of the sodium motor, form the T-ring structure attached to the LP ring in the periplasmic space. MotY has a putative peptidoglycan-binding motif in its C-terminal region and MotX...

The recombinant expression of soluble proteins in Escherichia coli continues to be a major bottleneck in structural genomics. The establishment of reliable protocols for the performance of small-scale expression and solubility testing is an essential component of structural genomic pipelines. The SSGCID Protein Production Group at the University of Washington (UW-PPG) has developed a high-throu...

BACKGROUND Functional Genomics, the systematic characterisation of the functions of an organism's genes, includes the study of the gene products, the proteins. Such studies require methods to express and purify these proteins in a parallel, time and cost effective manner. RESULTS We developed a method for parallel expression and purification of recombinant proteins with a hexahistidine tag (H...

A practically simple top-down process for the exfoliation of graphene (GN) and few-layer graphene (FLG) from graphite is described. We have discovered that a biocompatible amphiphilic pyrene-based hexahistidine peptide is able to exfoliate, functionalize, and dissolve few layer graphene flakes in pure water under exceptionally mild, sustainable and virtually innocuous low intensity cavitation c...

Many proteins that accumulate in the form of insoluble aggregates when they are overproduced in Escherichia coli can be rendered soluble by fusing them to E. coli maltose binding protein (MBP), and this will often enable them to fold in to their biologically active conformations. Yet, although it is an excellent solubility enhancer, MBP is not a particularly good affinity tag for protein purifi...

tolerance with the people with other beliefs is one of the ethical issues that are focused on in enlightenment europe. since lessing is known as a scout enlightenment in german literature so this article studies the concept of tolerance by him in the dramas minna von barnhelm and the jews. for this purpose, first the history of enlightenment europe from the beginning up to lessingʼs time that i...

Opinion There has been increasing interest in the field of medicine and in the social life of patients as well as health care providers in the realm of the media, namely, films and television shows. Table 1 lists some popular television series that are based on events germane to the medical field [1–7]. These shows constitute a genre in television, the ''medical drama. " A medical drama can be ...

This paper develops a new conception of organizational knowledge management as "knowledge ecology." The Socrates electronic learning environment is described as an example of a knowledge ecosystem for education and training. The Socrates program was developed as a knowledge management system, viewing classrooms as organizations for lifelong learning. Socrates allows even novice Web users to qui...

Abstract The author analyses the problem of weak will in Leo Tolstoy’s story Father Sergius . She ponders why protagonist, a man with such heightened awareness good and evil, at some point his life chooses evil. places ( akrasia ) first into context various iterations determinism subsequently considerations raised by Socrates Aristotle. As their answers are not fully applicable to titular chara...