A mathematical model was developed and tested to simulate the generation and transfer of heat in solid substrate fermentation (SSF). The experimental studies were realized in a 1-L static bioreactor packed with cassava wet meal and inoculated with Aspergillus niger. A simplified pseudohomogeneous monodimensional dynamic model was used for the energy balance. Kinetic equations taking into accoun...

Engineered tissue grafts have been manufactured using methods based predominantly on traditional labour-intensive manual benchtop techniques. These methods impart significant regulatory and economic challenges, hindering the successful translation of engineered tissue products to the clinic. Alternatively, bioreactor-based production systems have the potential to overcome such limitations. In t...

A new type of bioreactor for air pollution control has been developed. The new process relies on an organic-phase emulsion and actively growing pollutant-degrading microorganisms, made into a foam with the air being treated. This new reactor is referred to as a foamed emulsion bioreactor (FEBR). As there is no packing in the reactor, the FEBR is not subject to clogging. Mathematical modeling of...

The present work involves numerical simulation of a steady, incompressible forcedconvection fluid flow through a matrix of porous media between two parallel plates at constanttemperature. A Darcy model for the momentum equation was employed. The mathematical model forenergy transport was based on single phase equation model which assumes local thermal equilibriumbetween fluid and solid phases. ...

A continuous two-phase partitioning bioreactor (C-TPPB), operated with coiled tubing made of the DuPont polymer Hytrel 8206, was tested for the bioremediation of 4-chlorophenol, as a model toxic compound. The tubing was immersed in the aqueous phase, with the contaminated water flowing tube-side, and an adapted microbial culture suspended in the bioreactor itself, with the metabolic demand of t...

Nonpoint source nitrogen is recognized as a significant water pollutant worldwide. One of the major contributors is agricultural drainage line water. A potential method of reducing this nitrogen discharge to water bodies is the use of immobilized denitrifying sludge (IDS). Our objectives were to (1) produce an effective IDS, (2) determine the IDS reaction kinetics in laboratory column bioreacto...

This research evaluates the effects of the inoculum size and enzymatic activity on the concentration of ethanol obtained through the simultaneous saccharifi cation and fermentation of alkali-pretreated cassava stems. Other goals for this study include the determination and validation of the optimal conditions for and the evaluation of the process of ethanol production in a bioreactor. Alkaline-...

Citric acid production is generally carried out in an aqueous medium stirred tank reactors (STR), where the solubility of oxygen low and demand microbial cultures high. Thus, for this bioprocess, providing adequate mass transfer rate (OTR) from gas phase into culture main challenge bioreactor selection operation. In study, citric by Yarrowia lipolytica W29 crude glycerol, batch cultures, was pe...

The applicability of a sequencing batch two phase partitioning bioreactor (TPPB) to the biodegradation of a highly toxic compound, 2,4-dichlorophenol (DCP) (EC(50)=2.3-40 mgL(-1)) was investigated. A kinetic study of the individual process steps (DCP absorption into the polymer, desorption and biodegradation) was performed and, based on favourable absorption/desorption characteristics (DCP diff...