STUDY HYPOTHESIS Does induction of mitochondrial outer membrane permeabilization (MOMP) in vitro affect specific functional parameters of human spermatozoa? STUDY FINDING Our findings show that MOMP induction increases intracellular reactive oxygen species (ROS) and decreases mean sperm velocity but does not alter DNA integrity. WHAT IS KNOWN ALREADY MOMP in somatic cells is related to a va...

Studies of the reproductive biology of the nematode Caenorhabditis elegans are providing valuable insights into the evolution and diversity of reproductive strategies [1,2]. The successful production of progeny in any species also highlights many fundamental problems in cell biology. Research on the amoeboid sperm of nematodes addresses a number of issues of broad biological significance, inclu...

Received: Revised: Accepted: April 22, 2013 July 30, 2013 July 31, 2013 The present study was aimed to investigate the association of scrotal circumference (SC) with sperm production and semen quality in Sahiwal bulls. Mature semen donor bulls (n=76), 3 to 5 years old, were divided into three groups according to SC: GI, GII, and GIII with 28-30, 31-35, and >35 cm, respectively. Semen was collec...

The role of follicle-stimulating hormone (FSH) in the control of spermatogenesis is not well established in any species, including man. We studied the effect of an experimentally-induced, selective FSH deficiency on sperm production in normal men. After a 3-mo control period, five normal men received testosterone enanthate (T) 200 mg i. m. weekly to suppress luteinizing hormone (LH) and FSH, un...

infertility is one of the most stressful conditions amongst married couples. male factor infertility is implicated in almost half of these cases. recent advances in the field of reproductive medicine have focused the attention of many researchers to consider reactive oxygen species (ros) as one of the mediators of infertility causing sperm dysfunction. although, ros is involved in many physiolo...

The iron-limited Southern Ocean plays an important role in regulating atmospheric CO(2) levels. Marine mammal respiration has been proposed to decrease the efficiency of the Southern Ocean biological pump by returning photosynthetically fixed carbon to the atmosphere. Here, we show that by consuming prey at depth and defecating iron-rich liquid faeces into the photic zone, sperm whales (Physete...

OBJECTIVE This study evaluated the integrity of the chromatin structure, reactive oxygen species (ROS) levels, mitochondrial membrane potential (MMP), DNA damage and lipid peroxidation of semen samples from infertile men classified as unexplained infertility. METHODS Between February 2010 and July 2011 semen parameters and functional tests were evaluated in 10 subjects with proven fertility, ...

BACKGROUND The popularity of alpacas (Vicugna pacos) is increasing in Sweden as well as in other countries; however, knowledge about optimal management practices under Swedish conditions is still limited. The wide age range reported when the onset of puberty can occur, between 1 and 3 years of age, makes management decisions difficult and may be influenced by the conditions under which the alpa...