We report a novel treatment for giant congenital melanocytic nevi (GCMN) that involves the reuse of resected nevus tissue after high hydrostatic pressurization (HHP). However, the remaining melanin pigments in the inactivated nevus tissue pose a problem; therefore, we performed a long-term observation of the color change of inactivated nevus tissue after HHP. Pressurized nevus specimens (200 MP...

Aim. Secondary tumor rarely develops from epidermal nevus. We present a case of a metastasizing squamous cell carcinoma that developed in a solitary epidermal nevus. Case Report. An 82-years old Japanese female was presented with a red tumor on the left axilla. She reported that the tumor developed in a congenital epidermal nevus. A biopsy of the tumor showed that a well-differentiated squamous...

Lateral labial melanocytic nevus or mole has cosmetic value among young or middle aged Iranian ladies particularly those with fair complexion. I describe auto transplantation of a melanocytic nevus from a remote area of the body to lateral labial skin. After selection of a 3-mm nevus, both donor and recipient sites were anesthetized. A punch with a diameter comparable to the diameter of t...

BACKGROUND Dermatologists, paediatricians, and general practitioners are often consulted by worried parents for the evaluation of a cutaneous tumor. METHODS Selective literature review. RESULTS Only 1-2% of skin tumors excised in children turn out to be malignant when examined histologically. Warning signs of malignancy include rapid growth, firm consistency, diameter exceeding 3 cm, ulcera...

A 64-year-old white female presented with an asymptomatic brown-to-black nodular lesion located on her back in proximity (about 1.7 cm) to a surgical scar; indeed, the patient had developed a melanoma in situ on her back in 2010. She reported that the lesion had been present for two years (Figure 1). Family history of melanoma or other skin cancers were negative. On dermatoscopy, the lesion sho...

Verrucous epidermal nevi are hamartomatous lesions of the epidermis that, unlike other epidermal nevi (such as sebaceous nevus or nevus comedonicus), are rarely associated with malignant neoplasms. The majority of squamous cell carcinoma develop in linear or multiple epidermal nevus and rarely in solitary epidermal nevus. In general, the prognosis is favorable. We report a case of well-differen...

A 41-year-old woman with a complex congenital nevus that possessed features of both a blue nevus and a nevus of Ota is described. She was found to have melanotic hyperpigmentation of the underlying subcutaneous tissue and dura mater. Two separate melanomas developed in the tissues underlying her nevus (one in the subcutaneous tissue and another intracranially, arising from the dura).

In real-world extraction of signal from data we are not given the needed signal prediction-error filter (PEF). Claerbout has taken S, the PEF of the signal, to be that of the data, S ≈ D. Spitz takes it to be S ≈ D/N . Where noises are highly predictable in time or space, Spitz gets significantly better results. Theoretically, a reason is that the essential character of a PEF is contained where...

BACKGROUND Spitz/Reed nevi are melanocytic lesions that may mimic melanoma at clinical, dermatoscopic and histopathological levels. Management strategies of these lesions remain controversial. OBJECTIVES We aim a correlation among clinical-dermatoscopic and histological features of a series of Spitz/Reed nevi diagnosed during 7 years at the Department of Dermatology. METHODS Clinical, derma...

The article by Shapiro et al., which summarizes a survey of respondents on the words or phrases they use to identify the melanocytic nevus described by Clark et al. in 1978, shows that over 70% of The American Society of Dermatopathology (ASDP) members and nearly 85% of The American Academy of Dermatology (AAD) members preferred one of the following phrases: ‘‘dysplastic nevus’’, ‘‘nevus with a...