Spontaneous regression of some tumours is known to occur. We report here on a patient who developed lung and scalp metastases from renal cell carcinoma approximately 1 year after undergoing a radical nephrectomy. The lung metastasis was documented by computed tomography and histological examination. A spontaneous complete regression of the lung and scalp metastases occurred. Shortly after, howe...

I read the article "Complete spontaneous regression of Merkel cell carcinoma metastatic to the liver: Did lifestyle modifications and dietary supplements play a role?"(1) with great interest. Merkel cell carcinoma carries a significant rate of recurrence and mortality.(2) Though spontaneous regression of Merkel cell carcinoma has been well documented in the literature,(3) the potential that the...

family physician to our spine clinic for assessment of left-sided leg pain of six months’ duration. His history was significant only for a spontaneous onset of lumbar back pain noted immediately after awkward bending six months prior, followed two to three days later by severe leg pain, paresthesias and ankle weakness, consistent with an L5 radiculopathy. His initial leg pain had been so intens...

BACKGROUND Complete spontaneous regression of melanoma metastatic to the lungs is a rare event. OBJECTIVE To report a case of biopsy-proven melanoma metastatic to the lung with complete spontaneous regression. METHODS Multidisciplinary case report. RESULTS A 35-year-old white female was diagnosed with metastatic melanoma to the lung. A pleural biopsy confirmed the diagnosis. Partial spont...

OBJECTIVE Pediatric low-grade gliomas comprise a diverse range of central nervous system tumors, sharing the usual course of a slow progression in growth. In individual cases however, the natural history can be variable, and rarely spontaneous regression has been described. This paper describes factors associated with spontaneous regression. METHODS A literature review was performed to identi...

Spontaneous regression of primary malignant bone tumors is rare but has been reported in the human literature. To the authors' knowledge, spontaneous regression of primary bone tumors in dogs or cats has not been reported. Osteosarcoma (OSA) is the most common primary bone tumor in humans, and it has been reported that the incidence of OSA is 40 to 50 times greater in dogs than humans. In this ...

Spontaneous regression of metastatic malignant melanoma is rare. A case is presented here. The primary lesion, a lentigo maligna melanoma of the face, recurred after excision and metastasized to the parotid and upper cervical lymph nodes, and to the lungs. The patient declined further therapy. There was no clinical or radiologic evidence of metastasis 1 year later.

Intervertebral disc herniation of the lumbar spine is a common disease presenting with low back pain and involving nerve root radiculopathy. Some neurological symptoms in the majority of patients frequently improve after a period of conservative treatment. This has been regarded as the result of a decrease of pressure exerted from the herniated disc on neighboring neurostructures and a gradual ...