1 Ferguson A, Ziegler K. Intraepithelial lymphocyte mitosis in a jejunal biopsy correlates with intraepithelial lymphocyte count, irrespective of diagnosis. Gut 1986; 27: 675-9. 2 Niazi NM, Leigh RJ, Crowe P, Marsh MN. Morphometric analysis of small intestinal mucosa. I Methodology, epithelial volume compartments and enumeration of inter-epithelial space lymphocytes. Virchows Archiv [Pathol Ana...

One of the more mysterious and still rather poorly understood diseases seen in the tropical regions of the world is Tropical Sprue (TS). TS is a clinical syndrome with an unknown etiology typically characterized by an acquired chronic diarrheal illness, small bowel mucosal abnormalities and malabsorption resulting in nutritional deficiencies and weight loss [1]. These are vague symptoms which c...