Background: The aim of this retrospective study was to evaluate the therapeutic outcomes and organ preservation in patients with squamous cell carcinoma of the buccal mucosa treated with radiotherapy and retrograde superselective intra-arterial chemotherapy. Materials and Methods: Between April 2006 and March 2016, 28 patients (3 with stage II; 8 with stage III; and 17 with stage IV) with squam...

The accuracy of diagnosis in 656 patients with the four common histopathological types of primary lung cancer has been assessed by comparing the cell type diagnosis made on cytological and histological investigation with that determined by examination of the surgically resected or necroscopy specimen. The accuracy of diagnosis achieved by cytological examination of sputum and bronchial aspirate...

Introduction: Squamous cell carcinoma (SCC) is the most common head and neck malignancy. Smoking, alcohol consumption, viral infections, exposure, oral hygiene, and dietary, genetic, and occupational factors are the most important etiologic factors. The aim of this study was determining the incidence of etiologic factors in head and neck SCC.  Materials and Methods: This is a cross-sectiona...

PURPOSE To distinguish a metastasis from a second primary tumor in patients with a history of head and neck squamous cell carcinoma and subsequent pulmonary squamous cell carcinoma. EXPERIMENTAL DESIGN For 44 patients with a primary squamous cell carcinoma of the head and neck followed by a squamous cell carcinoma of the lung, clinical data, histology, and analysis of loss of heterozygosity (...

background and aims. helicobacter pylori is a microaerophilic gram-negative spiral organism. it is recognized as the etiologic factor for peptic ulcers, gastric adenocarcinoma and gastric lymphoma. recently, it has been isolated from dental plaque and the dorsum of the tongue. this study was designed to assess the association between h. pylori and oral lesions such as ulcerative/inflammatory le...

lichenoid reactions represent a family of lesions with different etiologic factors and a common clinical and histologic appearance. lichen planus is included with lichenoid reactions and is a relatively common chronic mucocutaneous disorder. the most important complication of lichenoid reactions is the possibility of malignant transformation. that is why it has been considered a precancerous co...

background and objective: esophageal cancer especially squamous cell carcinoma (scc) is one of the most common gastro intestinal malignancies in north part of iran (khorasan). the standard treatment for esophageal cancer is surgical resection, but its outcome remains poor. then, the oncologists try to treat this cancer with sandwich protocols especially neo-adjuvant chemo-radiotherapy. several ...

background and objective: human papillomavirus (hpv) is one of the possible etiologic factors  in development of esophageal squamous cell carcinoma (escc). in this study we aimed to study the  role of hpv in escc. patients and methods:in this study, 140 cases of escc were analyzed for the hpv dna by  polymerase chain reaction (pcr) using gp5+/gp6+ primers for l1 open reading frame (orf) to  am...

background: esophageal squamous cell carcinoma (escc) is one of the lethal cancers with a high incidence rate in asia. many genes including cyclin d1 and p16 play important role in its carcinogenesis. we aimed to analyze the expressions of cyclin d1 and p16 with the various clinicopathological characteristics of escc.   method: we examined 30 biopsy samples of escc for cyclin d1 and p16 protein...