Despite the presence of neural stem cells and ongoing neurogenesis in some regions of the adult mammalian brain, neurons are not replaced in most brain regions after injury. With the aim to unravel factors contributing to the failure of neurogenesis in the injured cerebral cortex, we examined the expression of cell fate determinants after acute brain injuries, such as stab wound or focal ischem...

This study pertains to the transition between selective neuronal necrosis and the development of cerebral infarction (pan-necrosis). We infused the neuron selective excitotoxin N-methyl-D-aspartate (NMDA) at a relatively high concentration (10 microliters of 50 mM NMDA in phosphate buffer, pH 7.4) into the rat cortex. Local injection of lactic acid and a minor stab wound in the cortex were used...

Ureterostomy: Under intravenous pentobarbitone (30mg/~g) anaesthesia the ureter is approached retroperitoneally through a paravertebral incision extending from the costovertebral angle to the iliac crest. The muscles of the abdominal wall are cut along the line of incision. The ureter is identified in the retroperitoneal tissue and is drawn out without disturbing its blood supply. A longitudina...

girl had some minor lacerations of the left hand and a single stab-wound in the upper abdomen. Under general anaesthesia, laparotomy was performed through an upper midline abdominal incision to reveal two holes in the stomach. 'These two wounds had resulted from the single stab-wound through the abdominal wall. The two defects were repaired in two layers. The stomach was noted empty at the time...

Current Opinion in Critical Care 2010, 16:609–617 Purpose of review Patients with penetrating abdominal trauma are at risk of harboring life-threatening injuries. Many patients are in need of emergent operative intervention. However, there are clearly patients who can be safely managed nonoperatively. This review evaluates the literature to identify management guidelines for patients with penet...

BACKGROUND This study was performed to determine the demographic and outcome of penetrating abdominal trauma in patients attending to emergency medicine department. MATERIALS AND METHODS This was a descriptive cross-sectional study in Imam Hossein Medical Center. Seventy five patients who came to our department with penetrating abdominal trauma during a 1 year period were enroled into this st...

RATIONALE Hepaticarterioportal fistula (APF) is a rare cause of portal hypertension and gastrointestinal hemorrhage, and presents as abnormal communication between the hepatic artery and portal vein. Percutaneous liver biopsy is a main iatrogenic cause of AFP. However, non-iatrogenic, abdominal, trauma-related APF is rarely reported. PATIENT CONCERNS A 29-year-old man presenting with severe, ...

The meeting of the Publication "Evidence Based Telemedicine - Trauma and Emergency Surgery" (TBE-CiTE), through literature review, selected three recent articles on the treatment of victims stab wounds to the abdominal wall. The first study looked at the role of computed tomography (CT) in the treatment of patients with stab wounds to the abdominal wall. The second examined the use of laparosco...