BACKGROUND Despite advances in medical practices, in recent decades permanent reductions in joint function have not been achieved, and the high mortality rate of patients with staphylococcal septic arthritis has not substantially improved. METHODS We evaluated the effects of a combined tumor necrosis factor (TNF) inhibitor and antibiotic therapy on the course of Staphylococcus aureus arthriti...

Food poisoning that involves multiple etiologies is reported from developing as well developed nations.Among the microbial causes, Staphylococcus aureus a major pathogen of food can occur in sporadic and epidemic form. It may cause life-threatening infections children, elderly, immunocompromised persons. Staphylococcal responsible for 241,000 cases United States annually. A variety foods, such ...

The Rockefeller University Press $30.00 J. Cell Biol. Vol. 209 No. 1 143–162 www.jcb.org/cgi/doi/10.1083/jcb.201407130 JCB 143 Correspondence to Chang-Duk Jun: [email protected] Abbreviations used in this paper: ABM, actin-binding motif; APB, actin polymerization buffer; APC, antigen-presenting cell; Arp2/3, Actin-related protein 2/3; CFSE, carboxyfluorescein succinimidyl ester; CH, calponin hom...

Exposure to bacterial superantigens, such as staphylococcal enterotoxin B (SEB), can lead to the induction of acute lung injury/acute respiratory distress syndrome (ALI/ARDS). To date, there are no known effective treatments for SEB-induced inflammation. In the current study we investigated the potential use of the hyaluronic acid synthase inhibitor 4-methylumbelliferone (4-MU) on staphylococca...

Interactions of LIGHT and its receptors, herpesvirus entry mediator on T cells and lymphotoxin beta receptor on stromal cells, are implicated in the regulation of lymphoid organogenesis, costimulation of T cells, and activation of dendritic cells. In this work we report that LIGHT-deficient mice had normal lymphoid organs with T cells and APCs that normally responded to Ag stimulation and norma...

Studies of staphylococcal food poisoning have been made difficult by the lack of an easy, reliable method for demonstrating the presence of an enterotoxin, elaborated by certain strains of Staphylococcus aureus (Micrococcus pyogenes). The commonly used laboratory animals (guinea pig, mouse, rabbit, rat) are rodents, which as a class lack the appropriate mechanism for vomiting. These animals, th...

BACKGROUND The underlying mechanism of atopic dermatitis (AD) exacerbated by Staphylococcus aureus has not been established. However, we demonstrated recently that the majority of S. aureus strains colonized in the skin of Korean AD patients carried genes encoding staphylococcal enterotoxin A (SEA) and/or toxic shock syndrome toxin-1 (TSST-1). OBJECTIVE To clarify the role of staphylococcal s...

It has been well established that bacterial superantigens lead to the induction and aggravation of chronic inflammatory skin diseases. We investigated the clinical significance of serum specific immunoglobulin E (lgE) to the staphylococcal superantigens staphylococcal enterotoxin A (SEA), staphylococcal enterotoxin B (SEB), and toxic shock syndrome toxin (TSST)-1 in patients with chronic urtica...

Domiati cheese is the most popular type of white soft in Egypt. Staphylococcus aureus a common microorganism that can easily contaminate during processing and distribution. Enterotoxigenic S. strains produce staphylococcal enterotoxins (SE) have been involved food poisoning outbreaks worldwide. The aim present study was to examine inhibitory effect yoghourt starter culture nickel oxide nanopart...

Abstract Staphylococcal enterotoxins (SE) are essential in human and animal infection food poisoning. This study analyzed ten genes ( sek, sel, sem, sen, seo, sep, seq, ser, ses , set ) encoding new staphylococcal enterotoxin isolated from animals humans by multiplex polymerase chain reaction (PCR). In Yogyakarta, Indonesia, samples cases (174 isolates), cattle (5 goats isolates) resulted a tot...