The crude methanolic extract of the roots of Cerbera odollam Gaertn. was evaluated for its possible antinociceptive, antibacterial and diuretic activities in animal models. At the dose of 250 and 500 mg/kg body weight, the extract showed a significant antinociceptive effect in acetic acid induced writhing in mice comparable to that produced by aspirin, used as standard drug (P<0.001).The extrac...

Piper solmsianum C. DC. var. solmsianum (Piperaceae) is a shrub commonly found in areas with wet tropical soils. Other Piper species have been used in folk medicine as antitumoral and antiseptic agents. We studied the crude methanolic extract, some organic fractions and compounds isolated from this plant for possible antimicrobial activity against Gram-positive and Gram-negative bacteria. The b...

Pantothenol is a provitamin of pantothenic acid (vitamin B5) that is widely used in healthcare and cosmetic products. This analog of pantothenate has been shown to markedly inhibit the phosphorylation activity of the prokaryotic type II pantothenate kinase of Staphylococcus aureus, which catalyzes the first step of the coenzyme A biosynthetic pathway. Since type II enzymes are found exclusively...

Paediatric Urinary Tract Infections are not uncommon, and having an episode of UTI in the early childhood leads to future complications. With ever-increasing antibiotic resistance, the treatment options become more restricted to reserved drugs. This study, including 509 patients and expanded over one year in a tertiary care hospital in Eastern India, tries to throw some light on the recent tren...

Biogenic amines (BAs) are important nitrogenous compounds formed mainly by decarboxylation of amino acids or amination and transamination aldehydes ketones. That have been detected in adjuvant, a fermented fish very used as condiments Côte d’Ivoire. The aim this study was to identify non-lactic acid bacteria (non-LAB) populations isolated adjuevan on MRS agar producing biogenic amines. Thus, no...

Total flavonoids contents and antibacterial activity of the extracts from the aerial parts of two Labiateae species, Nepeta menthoides Boiss. & Buhse and Thymus trautvetteri Klokov & Desj.-Shost. were determined. Quantitative determination of flavonoid contents was calculated in terms of quercetin equivalent in various extracts (50% methanol, chloroform and distilled water) by AlCl3 colorimetri...

BACKGROUND Staphylococcus saprophyticus is the second most common cause of urinary tract infection (UTI) in young women. Relatively little is known about risk factors for this infection including exposure to vaginal spermicides, which increases the risk of UTI caused by Escherichia coli. PATIENTS AND METHODS We conducted a case-control study in a large health maintenance organization Case pat...

The aim of this study is to determine antibiotic resistance patterns and slime production characteristics of coagulase-negative Staphylococci (CoNS) caused nosocomial bacteremia. A total of 200 CoNS strains were isolated from blood samples of patients with true bacteremia who were hospitalized in intensive care units and in other departments of Istanbul University Cerrahpasa Medical Hospital be...

OBJECTIVES This study focused on the correlation between geno- and phenotypic tests in the correct assessment of mecA-mediated methicillin resistance among coagulase-negative staphylococci (CoNS) and the further characterization of mecA-positive isolates. METHODS A total of 121 CoNS from cases of bovine mastitis were investigated for oxacillin susceptibility by disc diffusion and broth microd...