نتایج جستجو برای: stat
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Emerging evidences suggest Janus kinase (JAK)-signal transducer and activator of transcription (STAT) signaling pathway plays an important role in bone development and metabolism. Effects of JAK-STAT pathway on skeletal development are summarized based on skeletal phenotype of individual JAK and STAT gene knockout mouse. Furthermore, STAT3 has more profound effects on bone homeostasis compared ...
The canonical JAK-STAT signaling pathway transmits signals from the cell membrane to the nucleus, to regulate transcription of particular genes involved in development and many other physiological processes. It has been shown in Drosophila that JAK and STAT also function in a non-canonical mode, to regulate heterochromatin. This review discusses the non-canonical functioning of JAK and STAT, an...
The JAK/STAT signaling pathway is required for many processes including cytokine signaling, hematopoiesis, gliagenesis, and Drosophila segmentation. In this report we present evidence demonstrating that the JAK/STAT pathway is also central to the establishment of planar polarity during Drosophila eye development. We show that a localized source of the pathway ligand, Unpaired, is present at the...
JAK-STAT signaling is a highly conserved regulator of stem cells and their niches. Aberrant activation in hematopoietic stem cells is the underlying cause of a majority of myeloproliferative diseases. This review will focus on the roles of JAK-STAT activity in three different adult stem cell systems in Drosophila. Tightly controlled levels of JAK-STAT signaling are required for stem cell mainte...
We discuss the application of an effective field theory (EFT) which incorporates the chiral symmetry of QCD to Compton scattering from the proton and deuteron. We describe the chiral EFT analysis of the γp scattering database presented in our recent review [1], which gives: α E1 = 10.5± 0.5(stat)± 0.8(theory) , β (p) M1 = 2.7± 0.5(stat)± 0.8(theory), for the electric and magnetic dipole polariz...
We report the results of a search for T, CP, CPT, and violation in B0-B0 mixing using an inclusive dilepton sample collected by the BABAR experiment at the PEP-II factory. Using a sample of 232 x 10(6) BB pairs, we measure the T and CP violation parameter |q/p| - 1 = (-0.8 +/- 2.7(stat) +/- 1.9(syst) x 10(-3), and the CPT and CP parameters Imz = (13.9 +/- 7.3(stat) +/- 3.2(syst)) x 10(-3) and D...
Section 1711, act Oct. 10, 1951, ch. 479, title IV, § 401, 65 Stat. 377, related to authorization of amount for military assistance. Section 1712, acts Oct. 10, 1951, ch. 479, title IV, § 402, 65 Stat. 377; June 20, 1952, ch. 449, § 6, 66 Stat. 143, related to authorization of amount for technical assistance. Section 1713, act Oct. 10, 1951, ch. 479, title IV, § 403, as added June 20, 1952, ch....
The importance of Jak-Stat pathway signaling in regulating cytokine-dependent gene expression and cellular development/survival is well established. Nevertheless, advances continue to be made in defining Jak-Stat pathway effects on different cellular processes and in different organisms. This review focuses on recent advances in the field and highlights some of the most active areas of Jak-Stat...
Some taxonomic notes on the genus Oberea Dejean, 1835 from Asia (Coleoptera, Cerambycidae, Lamiinae)
In the current work, the following taxonomic changes of genus Oberea Dejean, 1835 are proposed: Oberea flavescens Breuning, 1947, rest. stat.; Oberea toi Gressitt, 1939, rest. stat.; Oberea sylvia Pascoe, 1858, rest. stat.; Oberea taiwana Matsushita, 1933 = Oberea taihokuensis Breuning, 1962, syn. n.; Oberea sumbana Breuning, 1961 = Oberea antennata Franz, 1972, syn. n.; Oberea brevithorax Gres...
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