Liposome encapsulated hemoglobin is being developed as an artificial resuscitative fluid for in vivo oxygen delivery. In the present report, we examine the effect of accumulation of liposome encapsulated hemoglobin on the structure of reticuloendothelial organs following administration of liposome encapsulated bovine hemoglobin in the normovolemic rat. We have also examined the administration o...

the method has been developed and validated for the determination of hydroquinone in liposomal formulation. the samples were dissolved in methanol and evaluated in 293 nm. the validation parameters such as linearity, accuracy, precision, specificity, limit of detection (lod) and limit of quantitation (loq) were determined. the calibration curve was linear in 1-50 µg /ml range of hydroquinone an...

Stealth game mechanics rely on a suitably difficult distribution of enemy observers, the placement of which is typically a manual process. Here we investigate an automatic process for placement of observer opponents. We use a Monte-Carlo approach to generate randomized enemy positions and motions and combine this with a stealth path-planning and analysis framework. This allows us to ensure feas...

One of the radiotherapy has boron neutron capture therapy (BNCT). They may make it easier to kill tumor cells with BNCT. In BNCT, it is important for boron agents, which have high selectively and high accumulation, to be introduced into tumor cells. To date, the main boron compounds used by the clinical study are sodium mercaptododecaborate (BSH) and pboronophenylalanine (BPA). But, there are n...

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, antinociceptive, and antipyretic activities. Liposomes have been shown to improve the therapeutic efficacy of encapsulated drugs. The present study was conducted to compare the antinociceptive properties between liposome-encapsulated and free-form diclofenac in vivo via different nociceptive assay model...

In order to effectively evade anti-malware solutions, Android malware authors are progressively resorting to automatic obfuscation strategies. Recent works have shown, on small-scale experiments, the possibility of evading anti-malware engines by applying simple obfuscation transformations on previously detected malware samples. In this paper, we provide a large-scale experiment in which the de...

equi-luminous materials Robert D. Batten, Frank H. Stillinger, and Salvatore Torquato Department of Chemical Engineering, Princeton University, Princeton, New Jersey 08544, USA Department of Chemistry, Princeton University, Princeton, New Jersey, 08544, USA Princeton Institute for the Science and Technology of Materials, Princeton University, Princeton, New Jersey 08544, USA Program in Applied ...

We used stealth assessment, embedded in a game called Use Your Brainz (a slightly modified version of Plants vs. Zombies 2), to measure middle-school students’ problem solving skills. We began by developing a problem solving competency model based on a review of the relevant literature. We then identified ingame indicators that would provide evidence about students’ levels on various problem-so...