The temporal sequence of cell division and differentiation is explicitly controlled for succession and synchrony of developmental events. In this study we describe how the Caenorhabditis elegans gene sel-7 specifies the L3 stage-specific fate of seam cells, which adopt temporal specificities at each of four larval stages. Loss of function of sel-7 causes reiteration of the L2 stage fate at the ...

This paper describes the development of an on-line quality inspection algorithm for detecting the surface defect “seam” generated in rolling processes. A feature-preserving “snake-projection” method is proposed for dimension reduction by converting the suspicious seam-containing images to one-dimensional sequences. Discrete wavelet transform is then performed on the sequences for feature extrac...

The purpose of the paper is to substantiate width barrier and yield pillars for application a new seam development scheme in conditions Alardinskaya mine (Russia). develops gas-bearing coal seams that are prone spontaneous combustion hazardous due rock bumps, which leads frequent accidents. analysis world experience mining being bumps showed safe with longwalls can be provided by system inter-p...

The double bond photoisomerization of fulvene has been studied with quantum dynamics calculations using the multi-configuration time-dependent Hartree method. Fulvene is a test case to develop optical control strategies based on the knowledge of the excited state decay mechanism. The decay takes place on a time scale of several hundred femtoseconds, and the potential energy surface is centered ...

Refolding aggregated proteins is essential in combating cellular proteotoxic stress. Together with Hsp70, Hsp100 chaperones, including Escherichia coli ClpB, form a powerful disaggregation machine that threads aggregated polypeptides through the central pore of tandem adenosine triphosphatase (ATPase) rings. To visualize protein disaggregation, we determined cryo-electron microscopy structures ...

Current face alignment algorithms can robustly find a set of landmarks along face contour. However, the landmarks are sparse and lack curve details, especially in chin and cheek areas where a lot of concave-convex bending information exists. In this paper, we propose a local to global seam cutting and integrating algorithm (L2GSCI) to extract continuous and accurate face contour. Our method wor...

Use of the serogroup B meningococcal capsular polysaccharide (MenB CP) as a vaccine is hampered by the presence of epitopes that cross-react with human polysialic acid. As non-cross-reactive, protective capsular epitopes have also been described, we set out to develop protein mimics of one of such epitopes using as a template a highly protective mAb (mAb Seam 3) raised against a chemically modi...

Coal seam gas (CSG) is the extraction of methane gas that is desorbed from the coal seam and brought to the surface using a dewatering and depressurisation process within the saturated coalbed. The extracted water is often referred to as co-produced CSG water. In this study, co-produced water from the coal seam of the Bowen Basin (QLD, Australia) was characterised by high concentration levels o...

In screens for mutants defective in vulval morphogenesis, multiple mutants were isolated in which the uterus and the vulva fail to make a proper connection. We describe five alleles that define the gene cog-2, for connection of gonad defective. To form a functional connection between the vulva and the uterus, the anchor cell must fuse with the multinucleate uterine seam cell, derived from uteri...

Traditional methods of coal seam gas drainage rely on the use of reservoir pressure reduction to promote gas desorption from the coal matrix. Studies in coal mining gas drainage operations, particularly in coal seams that are deeply undersaturated and have low permeability, found the rate of reservoir pressure reduction was prohibitively slow. In such conditions, lengthy production delays have ...