A current thrust in medical research is the development of a non-invasive method for detection, localization, and characterization of an arterial stenosis (a blockage or partial blockage in an artery). A method has been proposed to detect shear waves in the chest cavity which have been generated by disturbances in the blood flow resulting from a stenosis. In order to develop this methodology fu...

In this paper we examine the effect of mild stenosis on blood flow, in an irregular axisymmetric artery with oscillating pressure gradient. The Herschel-Bulkley fluid model has been utilized for this study. The combined influence of an asymmetric shape and surface irregularities of constriction has been explored in this computational study. An extensive quantitative analysis has been performed ...

BACKGROUND The effective orifice area (EOA) is the standard parameter for the clinical assessment of aortic stenosis severity. It has been reported that EOA measured by Doppler echocardiography does not necessarily provide an accurate estimate of the cross-sectional area of the flow jet at the vena contracta, especially at low flow rates. The objective of this study was to test the validity of ...

This work deals with the development and application of reduction strategies for real-time and many query problems arising in fluid dynamics, such as shape optimization, shape registration (reconstruction), and shape parametrization. The proposed strategy is based on the coupling between reduced basis methods for the reduction of computational complexity and suitable shape parametrizations – su...

Transcatheter aortic valve implantation (TAVI) has evolved as a routine procedure to treat selected high-risk patients with severe aortic stenosis. The new J-Valve prosthesis is designed for antegrade transapical implantation, it is characterized by a porcine aortic prosthesis attaching to a self-expandable Nitinol stent. The key feature of the device are three U-shape anatomically oriented dev...

Corrected systolic time intervals of the left ventricle: the interval between the onset of the Q wave and the first heart sound (Q-MI), isovolumic contraction time (IVCT), and left ventricular ejection time (LVET) have been measured by noninvasive techniques in 26 patients with valvular aortic stenosis and in 25 patients with idiopathic hypertrophic subaortic stenosis. The results were compared...

A shape of the unitary triangle versus a CP violating parameter δ depends on the phase conventions of the CKM matrix, because the CP violating parameter δ cannot directly be observed, so that it is not rephasing-invariant. In order to seek for a clue to the quark mass matrix structure and the origin of the CP violation, the dependence of the unitary triangle shape on the parameter δ is systemat...